The American education agenda suggests a clear commitment to the development of programs and practices to increase equitable participation in higher education. During a time when equity-based policy initiatives are under attack in the United States, governmental TRIO Programs remain one proven pathway for ensuring college preparedness and access for all students. Research reviewed in this article suggests TRIO educational opportunity programs have been successful in increasing both the higher education attendance rates and educational attainment of students from low-income, first-generation college, and underrepresented ethnic minority backgrounds. Given the increasing political debate and the recent U.S. Supreme Court ruling against voluntary school desegregation, TRIO Programs are now more critical than ever for extending higher educational opportunities to students from diverse social and economic backgrounds. Furthermore, these programs may provide a model for P-12 school leaders, individual institutions, and all education professionals interested in widening access to higher education for all of our country's citizens. This article provides an overview of TRIO educational opportunity programs, research related to the effectiveness of these programs, and recommendations for principals, teachers, and professional staff. (Contains 1 table.)