This dissertation used synthetic datasets, semi-synthetic datasets, and a real-world dataset from an educational intervention to compare the performance of 15 machine learning and multiple imputation methods to estimate the individual treatment effect (ITE). In addition, it examined the performance of five evaluation metrics that can be used to…

Spatio-temporal processes are ubiquitous and prevalent across disciplines. Understanding the mechanisms underlying processes and integrating this information into models is of great interest, as it can improve forecasting accuracy and align with scientific motivation. Examples of such models include Partial Differential Equation (PDE) Models or…

When a new student comes to play an educational game, how can we determine what content to give them such that they learn as much as possible? When a frustrated customer calls in to a helpline, how can we determine what to say to best assist them? When an ill patient comes in to the clinic, how do we determine what tests to run and treatments to…

Syntactic structures are unobserved theoretical constructs which are useful in explaining a wide range of linguistic and psychological phenomena. Language acquisition studies how such latent structures are acquired by human learners through many hypothesized learning mechanisms and apparatuses, which can be genetically endowed or of general…

Clinical Decision Support is one of the only aspects of health information technology that has demonstrated decreased costs and increased quality in healthcare delivery, yet it is extremely expensive and time-consuming to create, maintain, and localize. Consequently, a majority of health care systems do not utilize it, and even when it is…