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The Effects of Nucleosome Positioning and Chromatin Architecture on Transgene Expression
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Kempton, Colton E. – ProQuest LLC, 2017
Eukaryotes use proteins to carefully package and compact their genomes to fit into the nuclei of their individual cells. Nucleosomes are the primary level of compaction. Nucleosomes are formed when DNA wraps around an octamer of histone proteins and a nucleosome's position can limit access to genetic regulatory elements. Therefore, nucleosomes…
Descriptors: Genetics, Scaffolding (Teaching Technique), Undergraduate Students, College Instruction