Data in many growing fields has an underlying network structure that can be taken advantage of. In this dissertation we apply data and network science to problems in the domains of systems biology and healthcare. Data challenges in these fields include noisy, heterogeneous data, and a lack of ground truth. The primary thesis of this work is that…

Because many words of a language have more than one meaning, readers regularly need to disambiguate words during sentence comprehension. Using priming, eye-tracking, and event-related brain potentials, this thesis tested whether readers differently disambiguate words with semantically related meanings like "wire" and "cone,"…

In this thesis, we study the importance of background knowledge in relation extraction systems. We not only demonstrate the benefits of leveraging background knowledge to improve the systems' performance but also propose a principled framework that allows one to effectively incorporate knowledge into statistical machine learning models for…

Social media provide a multitude of opportunities for knowledge contribution and sharing. However, the content reliability issue has caused comprehensive attention, especially on credible social media, such as Wikipedia. Despite Wikipedia's success with the open editing model, dissenting voices give rise to unreliable content due to two…

This thesis work is mainly focused on two problems related to improving accessibility of information graphics for visually impaired users. The first problem is automated analysis of information graphics for information extraction and the second problem is multi-modal representations for accessibility. Information graphics are graphical…