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Direct linkMavor, David Carl – ProQuest LLC, 2017
Ubiquitin is essential for eukaryotic life and varies in only 3 amino acid positions between yeast and humans. However, recent deep sequencing studies indicate that ubiquitin is highly tolerant to single mutations. We hypothesized that this tolerance would be reduced by chemically induced physiologic perturbations. To test this hypothesis, a class…
Descriptors: Biochemistry, College Science, Graduate Students, Genetics
