This case study examines Makerere University through the lens of U.S. land-grant ideal and normative domains in order to provide a deeper understanding of global higher education. A case study uses multiple types of data to create a holistic perspective. As well as interviewing Makerere stakeholders representing diverse sectors, numerous documents and different types of media were analyzed enabling a triangulation of data. Six major themes emerged focusing on Makerere's aspiration to be a research-led institution, the impact of neoliberalism, challenges in undergraduate education, the importance of reputation and saga, the ever-present role of the Ugandan government, and the continuing effects of colonialism. These findings are discussed in relationship to the land-grant domains, in particular the tensions and contradictions which can result in university instability. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]