The likelihood for generalized linear models with covariate measurement error cannot in general be expressed in closed form, which makes maximum likelihood estimation taxing. A popular alternative is regression calibration which is computationally efficient at the cost of inconsistent estimation. We propose an improved regression calibration…

Functional and structural relationship alternatives to the standard "F"-test for analysis of covariance (ANCOVA) are discussed for cases when the covariate is measured with error. An approximate statistical test based on the functional relationship approach is preferred on the basis of Monte Carlo simulation results. (SLD)