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Noma, Hisashi; Hamura, Yasuyuki; Gosho, Masahiko; Furukawa, Toshi A. – Research Synthesis Methods, 2023
Network meta-analysis has been an essential methodology of systematic reviews for comparative effectiveness research. The restricted maximum likelihood (REML) method is one of the current standard inference methods for multivariate, contrast-based meta-analysis models, but recent studies have revealed the resultant confidence intervals of average…
Descriptors: Network Analysis, Meta Analysis, Regression (Statistics), Error of Measurement
Riley, Richard D.; Collins, Gary S.; Hattle, Miriam; Whittle, Rebecca; Ensor, Joie – Research Synthesis Methods, 2023
Before embarking on an individual participant data meta-analysis (IPDMA) project, researchers should consider the power of their planned IPDMA conditional on the studies promising their IPD and their characteristics. Such power estimates help inform whether the IPDMA project is worth the time and funding investment, before IPD are collected. Here,…
Descriptors: Computation, Meta Analysis, Participant Characteristics, Data
Wang, Chia-Chun; Lee, Wen-Chung – Research Synthesis Methods, 2019
A systematic review and meta-analysis is an important step in evidence synthesis. The current paradigm for meta-analyses requires a presentation of the means under a random-effects model; however, a mean with a confidence interval provides an incomplete summary of the underlying heterogeneity in meta-analysis. Prediction intervals show the range…
Descriptors: Meta Analysis, Computation, Statistical Analysis, Prediction