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Efthimiou, Orestis; White, Ian R. – Research Synthesis Methods, 2020
Standard models for network meta-analysis simultaneously estimate multiple relative treatment effects. In practice, after estimation, these multiple estimates usually pass through a formal or informal selection procedure, eg, when researchers draw conclusions about the effects of the best performing treatment in the network. In this paper, we…
Descriptors: Models, Meta Analysis, Network Analysis, Simulation
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Lin, Lifeng; Chu, Haitao – Research Synthesis Methods, 2018
In medical sciences, a disease condition is typically associated with multiple risk and protective factors. Although many studies report results of multiple factors, nearly all meta-analyses separately synthesize the association between each factor and the disease condition of interest. The collected studies usually report different subsets of…
Descriptors: Bayesian Statistics, Multivariate Analysis, Meta Analysis, Correlation
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Friede, Tim; Röver, Christian; Wandel, Simon; Neuenschwander, Beat – Research Synthesis Methods, 2017
Meta-analyses in orphan diseases and small populations generally face particular problems, including small numbers of studies, small study sizes and heterogeneity of results. However, the heterogeneity is difficult to estimate if only very few studies are included. Motivated by a systematic review in immunosuppression following liver…
Descriptors: Meta Analysis, Diseases, Medical Research, Research Problems