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Vo, Tat-Thang; Porcher, Raphael; Chaimani, Anna; Vansteelandt, Stijn – Research Synthesis Methods, 2019
Case-mix heterogeneity across studies complicates meta-analyses. As a result of this, treatments that are equally effective on patient subgroups may appear to have different effectiveness on patient populations with different case mix. It is therefore important that meta-analyses be explicit for what patient population they describe the treatment…
Descriptors: Case Studies, Meta Analysis, Research Problems, Medical Research