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Yuan Tian; Xi Yang; Suhail A. Doi; Luis Furuya-Kanamori; Lifeng Lin; Joey S. W. Kwong; Chang Xu – Research Synthesis Methods, 2024
RobotReviewer is a tool for automatically assessing the risk of bias in randomized controlled trials, but there is limited evidence of its reliability. We evaluated the agreement between RobotReviewer and humans regarding the risk of bias assessment based on 1955 randomized controlled trials. The risk of bias in these trials was assessed via two…
Descriptors: Risk, Randomized Controlled Trials, Classification, Robotics
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Moustgaard, Helene; Jones, Hayley E.; Savovic, Jelena; Clayton, Gemma L.; Sterne, Jonathan AC; Higgins, Julian PT; Hróbjartsson, Asbjørn – Research Synthesis Methods, 2020
Randomized clinical trials underpin evidence-based clinical practice, but flaws in their conduct may lead to biased estimates of intervention effects and hence invalid treatment recommendations. The main approach to the empirical study of bias is to collate a number of meta-analyses and, within each, compare the results of trials with and without…
Descriptors: Epidemiology, Evidence, Medical Research, Intervention