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Direct linkGünhan, Burak Kürsad; Röver, Christian; Friede, Tim – Research Synthesis Methods, 2020
Meta-analyses of clinical trials targeting rare events face particular challenges when the data lack adequate numbers of events for all treatment arms. Especially when the number of studies is low, standard random-effects meta-analysis methods can lead to serious distortions because of such data sparsity. To overcome this, we suggest the use of…
Descriptors: Meta Analysis, Medical Research, Drug Therapy, Bayesian Statistics
