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The Use of Fixed Study Main Effects in Arm-Based Network Meta-Analysis
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Hans-Peter Piepho; Laurence V. Madden; Emlyn R. Williams – Research Synthesis Methods, 2024
Methods of network meta-analysis (NMA) can be classified as arm-based and contrast-based approaches. There are several arm-based approaches, and some of these have been criticized because they recover inter-study information and hence do not obey the principle of concurrent control. Here, we point out that recovery of inter-study information in…
Descriptors: Meta Analysis, Models, Methods, Data Collection
A Framework to Characterise the Reproducibility of Meta-Analysis Results with Its Application to Direct Oral Anticoagulants in the Acute Treatment of Venous Thromboembolism
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Céline Chapelle; Gwénaël Le Teuff; Paul Jacques Zufferey; Silvy Laporte; Edouard Ollier – Research Synthesis Methods, 2024
The number of meta-analyses of aggregate data has dramatically increased due to the facility of obtaining data from publications and the development of free, easy-to-use, and specialised statistical software. Even when meta-analyses include the same studies, their results may vary owing to different methodological choices. Assessment of the…
Descriptors: Meta Analysis, Replication (Evaluation), Data Analysis, Statistical Analysis
Advice for Improving the Reproducibility of Data Extraction in Meta-Analysis
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Ivimey-Cook, Edward R.; Noble, Daniel W. A.; Nakagawa, Shinichi; Lajeunesse, Marc J.; Pick, Joel L. – Research Synthesis Methods, 2023
Extracting data from studies is the norm in meta-analyses, enabling researchers to generate effect sizes when raw data are otherwise not available. While there has been a general push for increased reproducibility in meta-analysis, the transparency and reproducibility of the data extraction phase is still lagging behind. Unfortunately, there is…
Descriptors: Replication (Evaluation), Data Collection, Meta Analysis, Computer Software
Calculating the Power of a Planned Individual Participant Data Meta-Analysis to Examine Prognostic Factor Effects for a Binary Outcome
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Rebecca Whittle; Joie Ensor; Miriam Hattle; Paula Dhiman; Gary S. Collins; Richard D. Riley – Research Synthesis Methods, 2024
Collecting data for an individual participant data meta-analysis (IPDMA) project can be time consuming and resource intensive and could still have insufficient power to answer the question of interest. Therefore, researchers should consider the power of their planned IPDMA before collecting IPD. Here we propose a method to estimate the power of a…
Descriptors: Data, Individual Characteristics, Participant Characteristics, Meta Analysis
Effect Estimates Can Be Accurately Calculated with Data Digitally Extracted from Interrupted Time Series Graphs
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Turner, Simon Lee; Korevaar, Elizabeth; Cumpston, Miranda S.; Kanukula, Raju; Forbes, Andrew B.; McKenzie, Joanne E. – Research Synthesis Methods, 2023
Interrupted time series (ITS) studies are frequently used to examine the impact of population-level interventions or exposures. Systematic reviews with meta-analyses including ITS designs may inform public health and policy decision-making. Re-analysis of ITS may be required for inclusion in meta-analysis. While publications of ITS rarely provide…
Descriptors: Quasiexperimental Design, Graphs, Accuracy, Computation
Practical Guidance for Using Multiple Data Sources in Systematic Reviews and Meta-Analyses (with Examples from the MUDS Study)
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Mayo-Wilson, Evan; Li, Tianjing; Fusco, Nicole; Dickersin, Kay – Research Synthesis Methods, 2018
Data for individual trials included in systematic reviews may be available in multiple sources. For example, a single trial might be reported in 2 journal articles and 3 conference abstracts. Because of differences across sources, source selection can influence the results of systematic reviews. We used our experience in the Multiple Data Sources…
Descriptors: Information Sources, Data Collection, Research Methodology, Meta Analysis