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Direct linkVan Lissa, Caspar J.; van Erp, Sara; Clapper, Eli-Boaz – Research Synthesis Methods, 2023
When meta-analyzing heterogeneous bodies of literature, meta-regression can be used to account for potentially relevant between-studies differences. A key challenge is that the number of candidate moderators is often high relative to the number of studies. This introduces risks of overfitting, spurious results, and model non-convergence. To…
Descriptors: Bayesian Statistics, Regression (Statistics), Maximum Likelihood Statistics, Meta Analysis
Hong, Hwanhee; Chu, Haitao; Zhang, Jing; Carlin, Bradley P. – Research Synthesis Methods, 2016
Bayesian statistical approaches to mixed treatment comparisons (MTCs) are becoming more popular because of their flexibility and interpretability. Many randomized clinical trials report multiple outcomes with possible inherent correlations. Moreover, MTC data are typically sparse (although richer than standard meta-analysis, comparing only two…
Descriptors: Bayesian Statistics, Meta Analysis, Outcomes of Treatment, Comparative Analysis
