The random-effects model, applied in most meta-analyses nowadays, typically assumes normality of the distribution of the effect parameters. The purpose of this study was to examine the performance of various random-effects methods (standard method, Hartung's method, profile likelihood method, and bootstrapping) for computing an average effect size…

Dependent effect sizes are ubiquitous in meta-analysis. Using Monte Carlo simulation, we compared the performance of 2 methods for meta-regression with dependent effect sizes--robust variance estimation (RVE) and 3-level modeling--with the standard meta-analytic method for independent effect sizes. We further compared bias-reduced linearization…