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Direct linkKarabatsos, George – Research Synthesis Methods, 2018
There is a growing concern that much of the published research literature is distorted by the pursuit of statistically significant results. In a seminal article, Ioannidis and Trikalinos (2007, "Clinical Trials") proposed an omnibus (I&T) test for significance chasing (SC) biases. This test compares the observed number of studies…
Descriptors: Nonparametric Statistics, Bayesian Statistics, Bias, Statistical Significance
Network Meta-Analysis of Disconnected Networks: How Dangerous Are Random Baseline Treatment Effects?
Béliveau, Audrey; Goring, Sarah; Platt, Robert W.; Gustafson, Paul – Research Synthesis Methods, 2017
In network meta-analysis, the use of fixed baseline treatment effects (a priori independent) in a contrast-based approach is regularly preferred to the use of random baseline treatment effects (a priori dependent). That is because, often, there is not a need to model baseline treatment effects, which carry the risk of model misspecification.…
Descriptors: Risk, Network Analysis, Meta Analysis, Outcomes of Treatment
