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Direct linkJansen, Katrin; Holling, Heinz – Research Synthesis Methods, 2023
In meta-analyses of rare events, it can be challenging to obtain a reliable estimate of the pooled effect, in particular when the meta-analysis is based on a small number of studies. Recent simulation studies have shown that the beta-binomial model is a promising candidate in this situation, but have thus far only investigated its performance in a…
Descriptors: Bayesian Statistics, Meta Analysis, Probability, Simulation
Caspar J. Van Lissa; Eli-Boaz Clapper; Rebecca Kuiper – Research Synthesis Methods, 2024
The product Bayes factor (PBF) synthesizes evidence for an informative hypothesis across heterogeneous replication studies. It can be used when fixed- or random effects meta-analysis fall short. For example, when effect sizes are incomparable and cannot be pooled, or when studies diverge significantly in the populations, study designs, and…
Descriptors: Hypothesis Testing, Evaluation Methods, Replication (Evaluation), Sample Size
Qi, Hongchao; Rizopoulos, Dimitris; Rosmalen, Joost – Research Synthesis Methods, 2023
The meta-analytic-predictive (MAP) approach is a Bayesian method to incorporate historical controls in new trials that aims to increase the statistical power and reduce the required sample size. Here we investigate how to calculate the sample size of the new trial when historical data is available, and the MAP approach is used in the analysis. In…
Descriptors: Sample Size, Computation, Meta Analysis, Bayesian Statistics
