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Qi, Hongchao; Rizopoulos, Dimitris; Rosmalen, Joost – Research Synthesis Methods, 2023
The meta-analytic-predictive (MAP) approach is a Bayesian method to incorporate historical controls in new trials that aims to increase the statistical power and reduce the required sample size. Here we investigate how to calculate the sample size of the new trial when historical data is available, and the MAP approach is used in the analysis. In…
Descriptors: Sample Size, Computation, Meta Analysis, Bayesian Statistics