Provides selected examples to illustrate the impact of computers in science. Indicates that the most important single factor that has affected and will continue to affect the use of computers in science is the steady advance of technology, especially in the areas of logic and memory. (JN)

Illustrates the state of the art in pyrolysis mass spectrometry techniques through applications in: (1) structural determination and quality control of synthetic polymers; (2) quantitative analysis of polymer mixtures; (3) classification and structural characterization of fossil organic matter; and (4) nonsupervised numerical extraction of…

Reviews the nature of computer networks and previews their development by focusing on ways they are useful to scientists and to science, including applications for remote computer access, electronic mail, bulletin boards, teleconferencing, file transfer, resource sharing, and imbedding nontextual communications. (JN)

Discusses recent developments in the instrumentation and practice of analytical scale operations. Emphasizes detection devices and procedures in gas chromatography, liquid chromatography, electrophoresis, supercritical fluid chromatography, and field-flow fractionation. (JN)

Discusses: (1) rationale for chemical sensors in process analysis; (2) existing types of process chemical sensors; (3) sensor limitations, considering lessons of chemometrics; (4) trends in process control sensors; and (5) future prospects. (JN)

Discusses developments in electrochemical instrumentation, including the role of computers, measurement/control instruments, present needs and future prospects. Indicates that microprocessors are used primarily for data processing, and that progress depends on noninstrumental factors such as electrode materials. (Author/JN)

Describes a National Science Foundation (NSF) initiative designed to broaden access to advanced computing facilities for university researchers not eligible to tap into federally subsidized networks. Rationale for and issues related to the initiative are also considered. (JN)

Distinguishes between computer hardware and software and discusses status of software, application development productivity, software production, and research directions. (JN)

Describes UNIX time-sharing operating system, including the program environment, software development tools, flexibility and ease of change, portability and other advantages, and five applications and three nonapplications of the system. (JN)

The National Academy of Sciences suggests models for biomedical research which include a biology-wide information system with computerized database accessible from a multitude of dimensions. Links could help discover whether toxic chemicals have effects similar to hormones. Commonalities from molecules to ecosystems might restructure available…

A linear photodiode array is used as the photodetector element in a new ultraviolet-visible detection system for high-performance liquid chromatography (HPLC). Using a computer network, the system processes eight different chromatographic signals simultaneously in real-time and acquires spectra manually/automatically. Applications in fast HPLC…

Computer applications in scientific instrumentation are traced from early data processing to modern computer-based instruments. Probable pathways toward instruments with increased "intelligence" include, among others, implementation of hierarchical computer networks and microprocessor controllers and the simplification of programing. The…

The expected thrust for theoretical chemistry in the next decade will be to combine knowledge of fundamental chemical steps/interactions with advances in chemical dynamics, irreversible statistical mechanics, and computer technology to produce simulations of chemical systems with reaction site competition. A sample simulation (using the enzyme…

General principles of computer graphics are reviewed, including discussions of display hardware, geometric modeling, algorithms, and applications in science, computer-aided design, flight training, communications, business, art, and entertainment. (JN)

Described is the history and use of computers in all phases of liberal arts education at Dartmouth College. Included are surveys of computer use by students, by instructors, and as an integral part of courses. (SL)