This three-day integrated 5E inquiry lesson that includes physics, engineering, and biology concepts, uses physical computing and photoplethysmography to learn about one's pulse. The main learning objective is to have students communicate how wave phenomena, like a pulse, can be analyzed using sensors, which is called physical computing. This lesson was piloted in two physics classes where students worked in small groups. Each group had an Arduino board and a single pulse sensor. This lesson highlights computational thinking as a fundamental science and engineering skill by allowing opportunities to visualize data, simulate phenomena, solve problems with computer code, and see how a body system functions.