Exercise physiology seems to be a course that students love or hate. Many physical education students and others involved in the related areas of health, teaching, recreation, dance, athletic training, fitness, and motor learning and development find this course a requirement at some point in their curriculum. Inquiry-based learning is an instructional method involving teaching through questions. This method was developed in response to a perceived failure of more traditional forms of instruction where students memorize facts presented in texts. Through inquiry-based learning the student is guided to an understanding of key content. In this approach the learner is engaged in formulating a response rather than just being given an answer. This article presents inquiry-based learning as a method of teaching applied to the subject of exercise physiology, with the goal of engaging students and teachers in more meaningful learning. Questions pertaining to exercise physiology concepts are posed and followed by the guided active learning experiences that can be presented in class using lab experiences and lab type experiences when lab facilities may not be available. (Contains 2 resources.)