Causal mediation analysis is a popular approach for investigating whether the effect of an exposure on an outcome is through a mediator to better understand the underlying causal mechanism. In recent literature, mediation analysis with multiple mediators has been proposed for continuous and dichotomous outcomes. In contrast, methods for mediation…

Cluster memberships associated with the mediation effect are often changed due to the temporal distance between the cause-and-effect variables in longitudinal data. Nevertheless, current practices in multilevel mediation analysis mostly assume a purely hierarchical data structure. A Monte Carlo simulation study is conducted to examine the…