Higher vocational education is developing vigorously, it is urgent to improve the teaching effect. In order to verify whether an optimized blended learning mode has a significant positive impact on the learning presence, learning attitude and motivation of vocational students, 92 vocational students from two teaching classes were taken as research objects to conduct a 3-month quasi-experimental study. Covariate analysis and paired sample T-test were used to process the pre-and post-test data, and it was found that the influence on the sense of presence was F=4.335, P=0.000<0.001, and the influence on learning attitude and motivation was F=3.957, P=0.000<0.05, both of which reached a significant level. It is concluded that the optimized blended learning model and simple blended learning model have significant positive effects on the learning presence, learning attitude and motivation of vocational students. Vocational colleges should vigorously promote blended learning optimized according to different courses, especially after the COVID-19 pandemic, which should become the new normal.