Neurofibromatosis Type 1 (NF1) is a common autosomal dominant single-gene disorder, in which the co-occurrence of autism spectrum disorder (ASD) has attracted considerable research interest recently with prevalence estimates of 21-40%. However, detailed characterization of the ASD behavioral phenotype in NF1 is still lacking. This study…

Background: Numerous studies have examined gene × environment interactions (G × E) in cognitive and behavioral domains. However, these studies have been limited in that they have not been able to directly assess differential patterns of gene expression in the human brain. Here, we assessed G × E interactions using two publically available datasets…

Research has supported the existence of distinct behavioral patterns, demographic correlates, and etiologic mechanisms for aggressive (AGG) versus nonaggressive but delinquent (DEL) antisocial behavior. Though behavioral genetic studies have the potential to further crystallize these dimensions, inconsistent results have limited their…

Considers the increase in research on adolescence, with attention to its transitional aspects during the adolescent period and as a bridge between childhood and adulthood. In addition, discusses the effort to examine interactional processes between parent and child and between environment and genes, with respect to the articles of this special…

Examined evidence for reciprocal influence between adoptive parents' behavior and heritable characteristics of adopted children. Found that psychiatric disorders of biological parents were significantly related to children's antisocial/hostile behaviors and consequently with adoptive parents' behavior. Also, the adoptee's antisocial/hostile…