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Rachel C. Branco; Holly V. Goodson; Erin M. Jonasson – Journal of Chemical Education, 2022
Case studies are helpful teaching tools that can bring scientific concepts to life. Here, we present a case study related to protein-ligand interactions, amino acids, protein structure, and protein modification. While protein-ligand interaction is a foundational concept within Biochemistry, there are few available case studies that focus on this…
Descriptors: Biochemistry, Science Instruction, Chemistry, Alzheimers Disease
Halpin, Catherine M.; Reilly, Ciara; Walsh, John J. – Journal of Chemical Education, 2010
The discovery that galantamine penetrates the blood-brain barrier has led to its clinical use in the treatment of choline-deficiency conditions in the brain, such as Alzheimer's disease. This experiment involves the isolation and structure elucidation of galantamine from "Leucojum aestivum". Isolation of the alkaloid constituents in "L. aestivum"…
Descriptors: Undergraduate Students, Alzheimers Disease, Brain, Science Experiments
King, Angela G. – Journal of Chemical Education, 2007
This article presents three reports of research advances. The first report describes a deoxyribonucleic acid (DNA)-based computer that could lead to faster, more accurate tests for diagnosing West Nile Virus and bird flu. Representing the first "medium-scale integrated molecular circuit," it is the most powerful computing device of its type to…
Descriptors: Scientific Research, Biochemistry, Genetics, Computers
Luehrs, Dean C.; Roher, Alex E. – Journal of Chemical Education, 2007
The study demonstrates the Fenton reaction, which is carried out using the Fenton reagent that is used for groundwater and soil remediation. The Fenton reaction can be implicated in DNA damage, Alzheimer's disease, cardiovascular disease and ageing in general.
Descriptors: Alzheimers Disease, Chemistry, Science Experiments, Laboratory Experiments
King, Angela G. – Journal of Chemical Education, 2006
Neurogenerative diseases like Alzheimer's disease and Parkinson's disease involve a transformation between two peptide and protein structures of alpha-helices and beta-sheets, where the peptide backbone can also participate in metal ion binding in addition to histidine residues. However, the complete absence of change in conformation of Coiled…
Descriptors: Alzheimers Disease, Neurological Impairments, Structural Analysis (Science), Organic Chemistry