NotesFAQContact Us
Collection
Advanced
Search Tips
Showing 1 to 15 of 25 results Save | Export
Peer reviewed Peer reviewed
Direct linkDirect link
Oruro, Enver Miguel; Pardo, Grace V. E.; Lucion, Aldo Bolten; Calcagnotto, Maria Elisa; Idiart, Marco A. P. – Learning & Memory, 2020
During the first ten postnatal days (P), infant rodents can learn olfactory preferences for novel odors if they are paired with thermo-tactile stimuli that mimic components of maternal care. After P10, the thermo-tactile pairing becomes ineffective for conditioning. The current explanation for this change in associative learning is the alteration…
Descriptors: Neonates, Animals, Olfactory Perception, Brain Hemisphere Functions
Peer reviewed Peer reviewed
Direct linkDirect link
Boisselier, Lise; Ferry, Barbara; Gervais, Rémi – Learning & Memory, 2017
The hippocampal formation has been extensively described as a key component for object recognition in conjunction with place and context. The present study aimed at describing neural mechanisms in the hippocampal formation that support olfactory-tactile (OT) object discrimination in a task where space and context were not taken into account. The…
Descriptors: Animals, Role, Brain Hemisphere Functions, Olfactory Perception
Peer reviewed Peer reviewed
Direct linkDirect link
Tong, Michelle T.; Kim, Tae-Young P.; Cleland, Thomas A. – Learning & Memory, 2018
Long-term fear memory formation in the hippocampus and neocortex depends upon brain-derived neurotrophic factor (BDNF) signaling after acquisition. Incremental, appetitive odor discrimination learning is thought to depend substantially on the differentiation of adult-born neurons within the olfactory bulb (OB)--a process that is closely associated…
Descriptors: Memory, Olfactory Perception, Role, Animals
Peer reviewed Peer reviewed
Direct linkDirect link
Roschlau, Corinna; Votteler, Angeline; Hauber, Wolfgang – Learning & Memory, 2016
Here we tested in rats effects of the procognitive drugs modafinil and methylphenidate on post-acquisition performance in an object-location paired-associates learning (PAL) task. Modafinil (32; 64 mg/kg) was without effect, while higher (9 mg/kg) but not lower (4.5 mg/kg) doses of methylphenidate impaired PAL performance. Likewise, higher but not…
Descriptors: Animals, Animal Behavior, Drug Use, Memory
Peer reviewed Peer reviewed
Direct linkDirect link
Huang, Yan-You; Lavine, Amir; Kandel, Denise B.; Yin, Deqi; Colnaghi, Luca; Drisaldi, Bettina; Kandel, Eric R. – Learning & Memory, 2014
The dentate gyrus (DG) of the hippocampus is critical for spatial memory and is also thought to be involved in the formation of drug-related associative memory. Here, we attempt to test an aspect of the Gateway Hypothesis, by studying the effect of consecutive exposure to nicotine and cocaine on long-term synaptic potentiation (LTP) in the DG. We…
Descriptors: Brain Hemisphere Functions, Drug Use, Memory, Associative Learning
Peer reviewed Peer reviewed
Direct linkDirect link
Grimes, Matthew T.; Powell, Maria; Gutierrez, Sandra Mohammed; Darby-King, Andrea; Harley, Carolyn W.; McLean, John H. – Learning & Memory, 2015
Here we examine the role of the exchange protein directly activated by cAMP (Epac) in ß-adrenergic-dependent associative odor preference learning in rat pups. Bulbar Epac agonist (8-pCPT-2-O-Me-cAMP, or 8-pCPT) infusions, paired with odor, initiated preference learning, which was selective for the paired odor. Interestingly, pairing odor with Epac…
Descriptors: Animals, Olfactory Perception, Biochemistry, Role
Peer reviewed Peer reviewed
Direct linkDirect link
Bisby, James A.; Burgess, Neil – Learning & Memory, 2014
The formation of associations between items and their context has been proposed to rely on mechanisms distinct from those supporting memory for a single item. Although emotional experiences can profoundly affect memory, our understanding of how it interacts with different aspects of memory remains unclear. We performed three experiments to examine…
Descriptors: Memory, Animals, Emotional Response, Affective Behavior
Peer reviewed Peer reviewed
Direct linkDirect link
Raccuglia, Davide; Mueller, Uli – Learning & Memory, 2013
Throughout the animal kingdom, the inhibitory neurotransmitter ?-aminobutyric acid (GABA) is a key modulator of physiological processes including learning. With respect to associative learning, the exact time in which GABA interferes with the molecular events of learning has not yet been clearly defined. To address this issue, we used two…
Descriptors: Learning Processes, Associative Learning, Olfactory Perception, Animals
Peer reviewed Peer reviewed
Direct linkDirect link
Diviney, Mairead; Fey, Dirk; Commins, Sean – Learning & Memory, 2013
Learning to navigate toward a goal is an essential skill. Place learning is thought to rely on the ability of animals to associate the location of a goal with surrounding environmental cues. Using the Morris water maze, a task popularly used to examine place learning, we demonstrate that distal cues provide animals with distance and directional…
Descriptors: Cues, Learning Processes, Task Analysis, Animals
Peer reviewed Peer reviewed
Direct linkDirect link
Madalan, Adrian; Yang, Xiao; Ferris, Jacob; Zhang, Shixing; Roman, Gregg – Learning & Memory, 2012
Heterotrimeric G(o) is an abundant brain protein required for negatively reinforced short-term associative olfactory memory in "Drosophila". G(o) is the only known substrate of the S1 subunit of pertussis toxin (PTX) in fly, and acute expression of PTX within the mushroom body neurons (MB) induces a reversible deficit in associative olfactory…
Descriptors: Associative Learning, Short Term Memory, Cognitive Processes, Animals
Peer reviewed Peer reviewed
Direct linkDirect link
Cromer, Jason A.; Machon, Michelle; Miller, Earl K. – Journal of Cognitive Neuroscience, 2011
The PFC plays a central role in our ability to learn arbitrary rules, such as "green means go." Previous experiments from our laboratory have used conditional association learning to show that slow, gradual changes in PFC neural activity mirror monkeys' slow acquisition of associations. These previous experiments required monkeys to repeatedly…
Descriptors: Stimuli, Prior Learning, Brain Hemisphere Functions, Animals
Peer reviewed Peer reviewed
Direct linkDirect link
Andreau, Jorge Mario; Funahashi, Shintaro – Brain and Cognition, 2011
The prefrontal cortex (PFC) is known to contribute to memory processes such as encoding representations into long-term-memory (LTM) and retrieving these representations from LTM. However, the details of the PFC's contribution to LTM processes are not well known. To examine the characteristics of the PFC's contribution to LTM processes, we analyzed…
Descriptors: Visual Stimuli, Memory, Brain Hemisphere Functions, Associative Learning
Peer reviewed Peer reviewed
Direct linkDirect link
Wells, Audrey M.; Lasseter, Heather C.; Xie, Xiaohu; Cowhey, Kate E.; Reittinger, Andrew M.; Fuchs, Rita A. – Learning & Memory, 2011
Contextual stimulus control over instrumental drug-seeking behavior relies on the reconsolidation of context-response-drug associative memories into long-term memory storage following retrieval-induced destabilization. According to previous studies, the basolateral amygdala (BLA) and dorsal hippocampus (DH) regulate cocaine-related memory…
Descriptors: Cocaine, Long Term Memory, Cognitive Processes, Animals
Peer reviewed Peer reviewed
Direct linkDirect link
Tort, Adriano B. L.; Komorowski, Robert; Kopell, Nancy; Eichenbaum, Howard – Learning & Memory, 2011
The association of specific events with the context in which they occur is a fundamental feature of episodic memory. However, the underlying network mechanisms generating what-where associations are poorly understood. Recently we reported that some hippocampal principal neurons develop representations of specific events occurring in particular…
Descriptors: Animals, Brain Hemisphere Functions, Context Effect, Correlation
Peer reviewed Peer reviewed
Direct linkDirect link
Martel, Guillaume; Hevi, Charles; Friebely, Olivia; Baybutt, Trevor; Shumyatsky, Gleb P. – Learning & Memory, 2010
Synaptically released Zn[superscript 2+] is a potential modulator of neurotransmission and synaptic plasticity in fear-conditioning pathways. Zinc transporter 3 (ZnT3) knock-out (KO) mice are well suited to test the role of zinc in learned fear, because ZnT3 is colocalized with synaptic zinc, responsible for its transport to synaptic vesicles,…
Descriptors: Conditioning, Memory, Fear, Brain Hemisphere Functions
Previous Page | Next Page »
Pages: 1  |  2