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Crombag, Hans S.; Johnson, Alexander W.; Zimmer, Anne M.; Zimmer, Andreas; Holland, Peter C. – Learning & Memory, 2010
Cannabinoid CB1 receptor is abundantly expressed throughout the CNS and is implicated in numerous physiological and behavioral functions, including appetite and feeding. In the present study, wild-type and CB1 heterozygous and homozygous knockout mice were tested on an instrumental outcome-selective devaluation task to assess changes in acquired…
Descriptors: Animal Behavior, Animals, Brain, Evaluation Methods
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Lombas, Andres S.; Kearns, David N.; Weiss, Stanley J. – Learning and Motivation, 2008
The present experiment compared the effects of a food-based conditioned inhibitor on food seeking vs. cocaine seeking behavior. In two groups of rats, the A+/AB- Pavlovian conditioned inhibition procedure was used to create a conditioned inhibitor for food. Then, for one group of rats (Food-Food Group), a click stimulus was established as an…
Descriptors: Behavior Modification, Cocaine, Classical Conditioning, Animals
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Lex, Anja; Hauber, Wolfgang – Learning & Memory, 2008
Pavlovian stimuli previously paired with food can markedly elevate the rate of food-reinforced instrumental responding. This effect, termed Pavlovian-instrumental transfer (PIT), depends both on general activating and specific cueing properties of Pavlovian stimuli. Recent evidence suggests that the general activating properties of Pavlovian…
Descriptors: Stimuli, Classical Conditioning, Reinforcement, Food
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Michel, Maximilian; Kemenes, Ildiko; Muller, Uli; Kemenes, Gyorgy – Learning & Memory, 2008
The cAMP-dependent protein kinase (PKA) is known to play a critical role in both transcription-independent short-term or intermediate-term memory and transcription-dependent long-term memory (LTM). Although distinct phases of LTM already have been demonstrated in some systems, it is not known whether these phases require distinct temporal patterns…
Descriptors: Classical Conditioning, Long Term Memory, Anatomy, Brain Hemisphere Functions