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Yuwen Hung; Allison Green; Caroline Kelberman; Schuyler Gaillard; James Capella; Nicole Rudberg; John D. E. Gabrieli; Joseph Biederman; Mai Uchida – Journal of Attention Disorders, 2024
Objective: Stimulant medications are the main treatment for Attention Deficit Hyperactivity Disorder (ADHD), but overall treatment efficacy in adults has less than a 60% response rate. This study aimed to identify neural and cognitive markers predictive of longitudinal improvement in response to stimulant treatment in drug-naïve adults with ADHD.…
Descriptors: Stimulants, Drug Therapy, Attention Deficit Hyperactivity Disorder, Adults
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Destin Groff; Wen-Jan Tuan; Kraig Holt; James R. Latronica; Curtis Bone – Journal of Attention Disorders, 2025
Introduction: Prescription stimulants are an effective FDA approved treatment for attention deficit hyperactivity disorder (ADHD) however their safety has come under scrutiny. Multiple studies demonstrate safe use in pediatric populations, but prescriptions are increasing to adults and it is not evident which comorbidities might place people at…
Descriptors: Heart Disorders, Stimulants, Attention Deficit Hyperactivity Disorder, Drug Therapy
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Antshel, Kevin M.; Parascandola, Theresa; Taylor, Lea E.; Faraone, Stephen V. – Journal of American College Health, 2021
Objective: The prevalence of stimulant medication misuse is rising in college students. Motivations to use stimulant medications differ from motivation to use other substances such as alcohol or cannabis. However, no previous research has examined the impact of achievement goal orientation on stimulant misuse in college students. Participants: 309…
Descriptors: College Students, Goal Orientation, Stimulants, Drug Abuse
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Froehlich, Tanya E.; Epstein, Jeffery N.; Nick, Todd G.; Melguizo Castro, Maria S.; Stein, Mark A.; Brinkman, William B.; Graham, Amanda J.; Langberg, Joshua M.; Kahn, Robert S. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: Because of significant individual variability in attention-deficit/hyperactivity disorder (ADHD) medication response, there is increasing interest in identifying genetic predictors of treatment effects. This study examined the role of four catecholamine-related candidate genes in moderating methylphenidate (MPH) dose-response. Method:…
Descriptors: Attention Deficit Hyperactivity Disorder, Rating Scales, Drug Therapy, Identification
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Faraone, Stephen V.; Glatt, Stephen J.; Bukstein, Oscar G.; Lopez, Frank A.; Arnold, L. Eugene; Findling, Robert L. – Journal of Attention Disorders, 2009
Objective: Methylphenidate is a leading first-line treatment for ADHD (AD/HD). This stimulant has long been suspected to adversely affect sleeping patterns of treated individuals, especially children. There are few studies on the effects of recently developed longer-acting methylphenidate treatments, such as once-daily oral or transdermal…
Descriptors: Sleep, Attention Deficit Hyperactivity Disorder, Severity (of Disability), Drug Therapy