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Direct linkScheithauer, Mindy; Call, Nathan A.; Lomas Mevers, Joanna; McCracken, Courtney E.; Scahill, Lawrence – Journal of Autism and Developmental Disorders, 2021
Elopement is a common and dangerous concern in autism spectrum disorder (ASD). There is evidence that behavior analytic treatments can successfully treat elopement, but the research is limited due to small samples and treatment components varying across studies. The current study evaluated the feasibility of studying a manualized intervention for…
Descriptors: Randomized Controlled Trials, Intervention, Behavior Problems, Children
Hirota, Tomoya; Deserno, Marie; McElroy, Eoin – Journal of Autism and Developmental Disorders, 2020
Irritability and aggression (IA) are highly prevalent in individuals with autism spectrum disorder (ASD). Although clinical correlates of IA in this population have been previously examined, findings from existing studies capturing symptoms as a set of latent variables do not fully explain meaningful associations between the symptoms themselves.…
Descriptors: Aggression, Antisocial Behavior, Autism, Pervasive Developmental Disorders
Chez, Michael; Kile, Shawn; Lepage, Christopher; Parise, Carol; Benabides, Bobbie; Hankins, Andrea – Journal of Autism and Developmental Disorders, 2020
Prior studies have demonstrated successful irritability treatment using dopaminergic antagonists in autistic patients. The purpose of this pilot study was to assess the effect of dextromethorphan/quinidine (DM/Q) in autistic adults (18-60 years of age). This was a randomized, blinded, crossover, study of 14 patients randomized to DM/Q or a placebo…
Descriptors: Outcomes of Treatment, Randomized Controlled Trials, Pilot Projects, Drug Therapy
González-Domenech, Pablo José; Díaz Atienza, Francisco; García Pablos, Carlos; Serrano Nieto, Sandra; Herreros Rodríguez, Óscar; Gutiérrez-Rojas, Luis; Martínez-Ortega, José María – Journal of Mental Health Research in Intellectual Disabilities, 2019
Introduction: Diet and dietary interventions have drawn considerable attention in the literature as etiopathogenic factors and therapeutic approaches to Autism Spectrum Disorders (ASD), respectively. The objective of this study was to determine the influence of a gluten-free, casein-free (GFCF) diet on the alterations of behavior in children and…
Descriptors: Dietetics, Behavior Problems, Children, Adolescents
Helverschou, Sissel Berge; Ludvigsen, Linn Beate; Hove, Oddbjørn; Kildahl, Arvid Nikolai – International Journal of Developmental Disabilities, 2021
Psychiatric disorders in individuals with co-occurring autism spectrum disorders (ASD) and intellectual disability (ID) are common, but diagnosis presents many challenges. The Psychopathology in Autism checklist (PAC) is among the very few instruments specifically developed for this group of individuals. The psychometric properties of the PAC…
Descriptors: Mental Disorders, Psychometrics, Autism, Pervasive Developmental Disorders
Taylor, Briana J.; Sanders, Kevin B.; Kyle, Marie; Pedersen, Kahsi A.; Veenstra-Vanderweele, Jeremy; Siegel, Matthew – Journal of Autism and Developmental Disorders, 2019
Psychiatric hospitalization of children with autism spectrum disorder (ASD) is common, but there is little comparative information available on different psychiatric hospital treatment models. Children with ASD ages 4-20 were enrolled upon admission to either a specialized (N = 53) or a general child psychiatric unit (N = 27). Caregivers completed…
Descriptors: Psychiatric Hospitals, Patients, Children, Adolescents
Lewis, Alan S.; van Schalkwyk, Gerrit Ian; Lopez, Mayra Ortiz; Volkmar, Fred R.; Picciotto, Marina R.; Sukhodolsky, Denis G. – Journal of Autism and Developmental Disorders, 2018
Nicotinic acetylcholine receptors (nAChRs), particularly the a7 nAChR, are implicated in the pathophysiology of both autism spectrum disorder (ASD) and aggressive behavior. We explored the feasibility, tolerability, and preliminary efficacy of targeting nAChRs using transdermal nicotine to reduce aggressive symptoms in adults with ASD. Eight…
Descriptors: Aggression, Adults, Stimulants, Pervasive Developmental Disorders
Sannar, Elise M.; Palka, Tamara; Beresford, Carol; Peura, Christine; Kaplan, Desmond; Verdi, Mary; Siegel, Matthew; Kaplan, Shir; Grados, Marco – Journal of Autism and Developmental Disorders, 2018
We examined the relationship between sleep duration and awakenings to Aberrant Behavior Checklist-Community (ABC-C) and Autism Diagnostic Observation Schedule (ADOS-2) scores in hospitalized youth with ASD and behavioral disturbance. Participants included 106 patients with a stay of at least 10 nights. Sleep in the hospital was recorded by staff…
Descriptors: Sleep, Correlation, Behavior Problems, Severity (of Disability)
Halvorsen, Marianne; Aman, Michael G.; Mathiassen, Børge; Brøndbo, Per Håkan; Steinsvik, Oddmar Ole; Martinussen, Monica – Journal of Mental Health Research in Intellectual Disabilities, 2019
Introduction: Although the Aberrant Behavior Checklist (ABC) is one of the most widely used behavioral rating scales among people with developmental disabilities, very few studies have examined the factor structure of the non-English versions. Methods: The construct validity of the Norwegian ABC was examined in a clinical sample of children and…
Descriptors: Foreign Countries, Check Lists, Behavior Problems, Psychometrics
Conner, Caitlin M.; White, Susan W.; Beck, Kelly B.; Golt, Josh; Smith, Isaac C.; Mazefsky, Carla A. – Autism: The International Journal of Research and Practice, 2019
Emotion regulation impairments are common among individuals with autism spectrum disorder and are believed to often underlie commonly seen problems with aggression, depression, and anxiety. The Emotional Awareness and Skills Enhancement program was developed to reduce emotion regulation impairment and thereby improve behavioral disturbance, via…
Descriptors: Self Control, Emotional Response, Autism, Pervasive Developmental Disorders
Bitsika, Vicki; Sharpley, Christopher F. – International Journal of Disability, Development and Education, 2017
The association between aberrant behaviour and depression was examined in a sample of 150 young males with Autism Spectrum Disorder via parent ratings on the Aberrant Behavior Checklist (ABC) and the Major Depressive Disorder subscale of the Child and Adolescent Symptom Inventory (CASI-4-D). Although several subscales of the ABC were significantly…
Descriptors: Behavior Problems, Depression (Psychology), Autism, Pervasive Developmental Disorders
Kaat, Aaron J.; Lecavalier, Luc; Aman, Michael G. – Journal of Autism and Developmental Disorders, 2014
The Aberrant Behavior Checklist (ABC) is a widely used measure in autism spectrum disorder (ASD) treatment studies. We conducted confirmatory and exploratory factor analyses of the ABC in 1,893 children evaluated as part of the Autism Treatment Network. The root mean square error of approximation was .086 for the standard item assignment, and in…
Descriptors: Validity, Children, Autism, Pervasive Developmental Disorders
Siegel, Matthew; Milligan, Briana; Chemelski, Bruce; Payne, David; Ellsworth, Beth; Harmon, Jamie; Teer, Olivia; Smith, Kahsi A. – Journal of Autism and Developmental Disorders, 2014
Psychiatric hospitalization of children with autism spectrum disorder and/or intellectual disability is common, however, the effectiveness of this intervention is largely unknown. Thirty-eight clinically-referred children 8-19 years old admitted to a specialized inpatient psychiatry unit were assessed by a consistent caregiver on the Aberrant…
Descriptors: Children, Hospitalized Children, Autism, Pervasive Developmental Disorders
Scahill, Lawrence; Aman, Michael G.; Lecavalier, Luc; Halladay, Alycia K.; Bishop, Somer L.; Bodfish, James W.; Grondhuis, Sabrina; Jones, Nancy; Horrigan, Joseph P.; Cook, Edwin H.; Handen, Benjamin L.; King, Bryan H.; Pearson, Deborah A.; McCracken, James T.; Sullivan, Katherine Anne; Dawson, Geraldine – Autism: The International Journal of Research and Practice, 2015
Restricted interests and repetitive behaviors vary widely in type, frequency, and intensity among children and adolescents with autism spectrum disorder. They can be stigmatizing and interfere with more constructive activities. Accordingly, restricted interests and repetitive behaviors may be a target of intervention. Several standardized…
Descriptors: Autism, Pervasive Developmental Disorders, Behavior Problems, Repetition
Erickson, Craig A.; Wink, Logan K.; Early, Maureen C.; Stiegelmeyer, Elizabeth; Mathieu-Frasier, Lauren; Patrick, Vanessa; McDougle, Christopher J. – Journal of Autism and Developmental Disorders, 2014
Rationale: An excitatory/inhibitory (E:I) imbalance marked by enhanced glutamate and deficient gamma-aminobutyric acid (GABA) neurotransmission may contribute to the pathophysiology of autism spectrum disorders (ASD). Objectives: We report on the first single-blind placebo lead-in trial of acamprosate, a drug with putative mechanisms restoring E:I…
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Metabolism
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