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Gugsa, Nishan; Schoenbaum, Geoffrey; Burke, Kathryn A.; Franz, Theresa M. – Learning & Memory, 2006
Psychostimulant exposure has been shown to cause molecular and cellular changes in prefrontal cortex. It has been hypothesized that these drug-induced changes might affect the operation of prefrontal-limbic circuits, disrupting their normal role in controlling behavior and thereby leading to compulsive drug-seeking. To test this hypothesis, we…
Descriptors: Conditioning, Fear, Scientific Research, Scientific Methodology