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Fish Oil Supplementation in Pregnancy and Neurodevelopment in Childhood--A Randomized Clinical Trial
Direct linkSass, Laerke; Bjarnadóttir, Elín; Stokholm, Jakob; Chawes, Bo; Vinding, Rebecca K.; Mora-Jensen, Anna-Rosa C.; Thorsen, Jonathan; Noergaard, Sarah; Ebdrup, Bjørn H.; Jepsen, Jens R.M.; Fagerlund, Birgitte; Bønnelykke, Klaus; Lauritzen, Lotte; Bisgaard, Hans – Child Development, 2021
A double-blind randomized controlled trial of n-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation or matching placebo during third trimester of pregnancy was conducted within the COPSAC[subscript 2010] mother-child cohort consisting of 736 women and their children. The objective was to determine if maternal n-3 LCPUFA pregnancy…
Descriptors: Pregnancy, Randomized Controlled Trials, Prenatal Influences, Mothers
Conradt, Elisabeth; Abar, Beau; Lester, Barry M.; LaGasse, Linda L.; Shankaran, Seetha; Bada, Henrietta; Bauer, Charles R.; Whitaker, Toni M.; Hammond, Jane A. – Child Development, 2014
Children chronically exposed to stress early in life are at increased risk for maladaptive outcomes, though the physiological mechanisms driving these effects are unknown. Cortisol reactivity was tested as a mediator of the relation between prenatal substance exposure and/or early adversity on adaptive and maladaptive outcomes. Data were drawn…
Descriptors: At Risk Persons, Stress Variables, Physiology, Metabolism
Yumoto, Chie; Jacobson, Sandra W.; Jacobson, Joseph L. – Child Development, 2008
Two models of vulnerability to socioenvironmental risk were examined in 337 African American children (M = 7.8 years) recruited to overrepresent prenatal alcohol or cocaine exposure: The cumulative risk model predicted synergistic effects from exposure to multiple risk factors, and the fetal patterning of disease model predicted that prenatal…
Descriptors: African American Children, At Risk Persons, Risk, Prenatal Influences
Peer reviewedDiPietro, Janet A.; And Others – Child Development, 1996
Examined fetal heart rate and movement in 31 healthy fetuses from 20 weeks through birth and at age 6 months. Found that more active fetuses were more difficult, unpredictable, unadaptable, and active as infants that were less active fetuses, and that higher fetal heart rate was associated with lower emotional tone, activity level, and…
Descriptors: Affective Behavior, Behavior Problems, Heart Rate, Infant Behavior
Wakschlag, Lauren S.; Leventhal, Bennett L.; Pine, Daniel S.; Pickett, Kate E.; Carter, Alice S. – Child Development, 2006
There is a robust association between prenatal smoking and disruptive behavior disorders, but little is known about the emergence of such behaviors in early development. The association of prenatal smoking and hypothesized behavioral precursors to disruptive behavior in toddlers (N=93) was tested. Exposed toddlers demonstrated atypical behavioral…
Descriptors: Cues, Developmental Psychology, Psychopathology, Prenatal Influences
Seifer, Ronald; LaGasse, Linda L.; Lester, Barry; Bauer, Charles R.; Shankaran, Seetha; Bada, Henrietta S.; Wright, Linda L.; Smeriglio, Vincent L.; Liu, Jing – Child Development, 2004
Attachment status of children exposed in utero to cocaine, opiates, and other substances was examined at 18 months (n=860) and 36 months (n=732) corrected age. Children exposed to cocaine and opiates had slightly lower rates of attachment security (but not disorganization), and their insecurity was skewed toward ambivalent, rather than avoidant,…
Descriptors: Security (Psychology), Personality, Child Behavior, Caregiver Attitudes
