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Davis, Michael; Myers, Karyn M.; Ressler, Kerry J. – Learning & Memory, 2006
Fear extinction is defined as a decline in conditioned fear responses (CRs) following nonreinforced exposure to a feared conditioned stimulus (CS). Behavioral evidence indicates that extinction is a form of inhibitory learning: Extinguished fear responses reappear with the passage of time (spontaneous recovery), a shift of context (renewal), and…
Descriptors: Fear, Epidemiology, Behavioral Science Research, Conditioning
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Janus, Christopher – Learning & Memory, 2004
TgCRND8 mice represent a transgenic mouse model of Alzheimer's disease, with onset of cognitive impairment and increasing amyloid-[beta] plaques in their brains at 12 weeks of age. In this study, the spatial memory in 25- to 30-week-old TgCRND8 mice was analyzed in two reference and one working memory Morris water maze (MWM) tests. In reference…
Descriptors: Pathology, Nonverbal Learning, Spatial Ability, Learning Strategies