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Direct linkSandstrom, Andrea; Daoust, Andrew R.; Russell, Evan; Koren, Gideon; Hayden, Elizabeth P. – European Journal of Developmental Psychology, 2021
Hypothalamic-Pituitary-Adrenal (HPA) axis activity is related to negative mental health outcomes, including depression. Most developmental research uses salivary cortisol to index HPA activity; however, hair cortisol concentrations (HCCs) reflect cortisol production over extended periods of time. While HCCs have been linked to adult depression,…
Descriptors: Females, Young Children, Predictor Variables, Depression (Psychology)
Nadja Rita Ging-Jehli; Deepa Manda; Jill Hollway; Elizabeth Hurt; Stacey Moone; L. Eugene Arnold – Journal of Developmental and Physical Disabilities, 2021
This pilot placebo-controlled trial (NCT00965068, 07/28/2009) explored effects of cholesterol supplementation on autism spectrum disorder (ASD) symptoms in children with abnormally low cholesterol. Fifteen children age 4-12 with ASD and cholesterol <5th percentile for age/sex were randomized to 225 mg cholesterol vs. matched placebo twice daily…
Descriptors: Pilot Projects, Biochemistry, Rating Scales, Autism Spectrum Disorders
Kryski, Katie R.; Dougherty, Lea R.; Dyson, Margaret W.; Olino, Thomas M.; Laptook, Rebecca S.; Klein, Daniel N.; Hayden, Elizabeth P. – Developmental Science, 2013
While activation of the hypothalamic-pituitary-adrenal (HPA) axis is an adaptive response to stress, excessive HPA axis reactivity may be an important marker of childhood vulnerability to psychopathology. Parenting, including parent affect during parent-child interactions, may play an important role in shaping the developing HPA system; however,…
Descriptors: Child Rearing, Self Control, Affective Behavior, Parent Child Relationship
