Biochemistry textbooks often provide a disconnected, highly mathematical, and decontextualized treatment of thermodynamic and kinetic principles, which renders topics like protein folding difficult to teach. This is concerning given that graduates entering careers, like the pharmaceutical industry, must be able to apply such knowledge and related…

A course-based undergraduate research experience (CURE) is a teaching approach aimed at developing students' ability to conduct novel research. Although students' perceptions of their learning during CUREs may not reflect actual student learning, such surveys provide a convenient and useful metric for course evaluation. Instructors can use survey…

Several course-based undergraduate research experiences (CUREs) have been published in the literature. However, only limited attempts have been made to rigorously identify the discovery-type research abilities that students actually develop during such experiences. Instead, there has been a greater focus on technical or procedural-type knowledge…

To keep biochemistry instruction current and relevant, it is crucial to expose students to cutting-edge scientific research and how experts reason about processes governed by thermodynamics and kinetics such as protein folding and dynamics. This study focuses on how experts explain their research into this topic with the intention of informing…

Course-based undergraduate research experiences (CUREs) have been described in a range of educational contexts. Although various anticipated learning outcomes (ALOs) have been proposed, processes for identifying them may not be rigorous or well documented, which can lead to inappropriate assessment and speculation about what students actually…

External representations (ERs), such as diagrams, animations, and dynamic models are vital tools for communicating and constructing knowledge in biochemistry. To build a meaningful understanding of structure, function, and process, it is essential that students become visually literate by mastering key cognitive skills that are essential for…

The aim of this research was to develop a model of factors affecting students' ability to interpret external representations (ERs) in biochemistry. The study was qualitative in design and was guided by the modelling framework of Justi and Gilbert. Application of the process outlined by the framework, and consultation with relevant literature, led…

The term "conceptual understanding" has been used rather loosely over the years in educational practice, with a tendency to focus on a few aspects of an extremely complex phenomenon. In this first article of a two-part miniseries on conceptual understanding, we describe the nature of expert (versus novice) knowledge and show how the conceptual…

The first paper in this two-part miniseries on conceptual understanding discussed expert and novice conceptual knowledge, the multifaceted nature of conceptual understanding, and the cognitive skills essential for constructing it. This second article presents examples of instruments for the assessment and development of five facets of conceptual…

There is a large body of educational research results available in the science education literature that could be usefully applied for the improvement of teaching practice in biochemistry and molecular biology. Unfortunately, for a great variety of reasons, such applications are relatively limited in our discipline. In this first paper in the…

Student assessment, in all its forms, is central to the educational process. In this paper in the series, "Bridging the Gap", I describe how assessment can be used as a powerful instrument for influencing how and what students learn and how and what instructors teach in a manner that is conducive to educationally sound curriculum change…

Visualization is an essential skill for all students and biochemists studying and researching the molecular and cellular biosciences. In this study, we discuss the nature and importance of visualization in biochemistry education and argue that students should be explicitly taught visual literacy and the skills for using visualization tools as…

Diagrams are considered to be invaluable teaching and learning tools in biochemistry, because they help learners build mental models of phenomena, which allows for comprehension and integration of scientific concepts. Sometimes, however, students experience difficulties with the interpretation of diagrams, which may have a negative effect on their…