Many proteins use transition metals, exploiting their properties to achieve particular metabolic effects. Some of these functions are well known, such as the use of iron and copper in oxygen redox chemistry, molybdenum in nitrogen reduction and zinc in the nucleophilic activation of water. I review these examples alongside some lesser-known…

Seaweed is rich in iodine, an essential component for the formation of thyroid hormones. Iodine deficiency is still a problem in the 21st century despite iodination programmes. Without sufficient iodine in the diet, we risk a decline in brain development and growth in fetuses and children. This key micronutrient is essential for the formation for…

Every day we deal with chemistry in various forms, but sometimes we don't see that. An example is biosensors that help us to evaluate health conditions, monitor environmental pollution and ensure food freshness. The most well known (and most widely sold) is the biosensor for blood glucose measurement, used every day by people with diabetes.…

The physical and chemical properties of Milk of Magnesia provide examples of chemical concepts and opportunities for investigative practical work for secondary chemistry students of all ages. Basing the lesson on the contents of that familiar blue bottle, which is probably lurking somewhere in a cupboard in most households, also showcases the role…

There is much more to science education than the requirements demanded by the examination curriculum. This article illustrates one example of an in-depth investigation, kick started with a Royal Society Partnership Grant, into essential oils as antimicrobial agents. The project and subsequent extensions were selected to be presented at various…

For many years biologists supposed that one group of microorganisms, which they called archaebacteria, were an ancient and primitive type of bacteria. Following biochemical analysis of their RNA and other cell components, it soon became clear that their distinct features merited classification in a separate domain, the archea. From an evolutionary…

The "droso4schools" project aims to introduce the fruit fly "Drosophila" as a powerful modern teaching tool to convey curriculum-relevant specifications in biology lessons. Flies are easy and cheap to breed and have been at the forefront of biology research for a century, providing unique conceptual understanding of biology and…

The relationship between the structure and function of proteins is an important area in biochemistry. Pupils studying A-level Biology are introduced to the four levels of protein structure (primary, secondary, tertiary and quaternary) and how these can be used to describe the progressive folding of a chain of amino acid residues to a final,…

One of the striking characteristics of fundamental biological processes, such as genetic inheritance, development and primary metabolism, is the limited amount of variation in the molecules involved. Natural selective pressures act strongly on these core processes and individuals carrying mutations and producing slightly sub-optimal versions of…

The reconstruction of ancient atmospheric carbon dioxide concentrations is essential to understanding the history of the Earth and life. It is also an important guide to identifying the sensitivity of the Earth system to this greenhouse gas and, therefore, constraining its future impact on climate. However, determining the concentration of…

Reviews the origins of the biochemical process industries, traces their development from cottage to industrial scale, and suggests the developmental trends that are likely to occur. (AL)

Describes types of industrial techniques involving biochemical products, specifying the advantages and disadvantages of batch and continuous processes, and contrasting biochemical and chemical engineering. See SE 506 318 for Part I. (AL)

Compares differences in function and behavior of two oxygen-binding proteins, myoglobin found in muscle and hemoglobin found in blood. Describes the mechanism of oxygen-binding and allosteric effect in hemoglobin; also describes the effect of pH on the affinity of hemoglobin for oxygen. (CS)

Short articles describing a model of protein synthesis, a simple constant temperature incubator, techniques for determining the age structure of populations from qualitative characters, an experimental demonstration of proteolytic enzyme action, and apparatus for demonstrating hydrotrophic response of roots and for measuring photosynthetic rate of…