This article describes a laboratory protocol for a multiweek project piloted in a new upper-level biology laboratory (BIO 426) using cell culture techniques. Human embryonic kidney-293 cells were used, and several culture media and supplements were identified for students to design their own experiments. Treatments included amino acids, EGF,…

This laboratory exercise investigates the phenomenon of cytoplasmic streaming in the fresh water alga "Nitella". Students use the fungal toxin cytochalasin D, an inhibitor of actin polymerization, to investigate the mechanism of streaming. Students use simple statistical methods to analyze their data. Typical student data are provided. (Contains 3…

This study used a mixed methods approach to evaluate hybrid peer-assisted learning approaches incorporated into a bioinformatics tutorial for a genome annotation research project. Quantitative and qualitative data were collected from undergraduates who enrolled in a research-based laboratory course during two different academic terms at UCLA.…

Many students do not recognize that individual organisms within populations vary, and this may make it difficult for them to recognize the essential role variation plays in natural selection. Also, many students have weak scientific reasoning skills, and this makes it difficult for them to recognize misconceptions they might have. This paper…

A physical model was used in a laboratory exercise to teach students about countercurrent exchange mechanisms. Countercurrent exchange is the transport of heat or chemicals between fluids moving in opposite directions separated by a permeable barrier (such as blood within adjacent blood vessels flowing in opposite directions). Greater exchange of…

Describes the use of student projects within a traditional biology laboratory class to incorporate openness, inquiry techniques, and student choice into course teaching. Included is a list of sample investigations. (CC)

A microarray experiment is presented that, in six laboratory sessions, takes undergraduate students from the tissue sample right through to data analysis. The model chosen, the murine erythroleukemia cell line, can be easily cultured in sufficient quantities for class use. Large changes in gene expression can be induced in these cells by…

Reported is the analysis of an individualized biology laboratory program in order to determine if objectives of the laboratory were achieved by students and to identify factors related to success in an individualized laboratory. (Author/PB)

Examined is the use of the microcomputer as a tutor, for simulations of experiments, and to provide graphic interpretations of abstract concepts in the college biology setting. Discussed are computer enhanced courses being used, the software library, and the computer laboratory facility. Lists reasons for adoption of computer enhanced format. (MVL)

A hands-on approach to science is highly desirable because an inquiry approach to science greatly promotes learning. However when students and teachers manipulate glassware, chemical, and other materials, accidents will happen. Because of this, risk management and safety procedures become an important, integral part of the science curriculum. This…