Stem cell therapy, a cutting-edge technology, aims to replace damaged cells with healthy ones. Stem cells possess the remarkable ability to multiply and differentiate into various cell types, making them ideal candidates for regenerative medicine. This therapy holds promise for treating a wide range of conditions and injuries. In this review, I…

This article reviews the discovery of RNA interference, its mechanism of action and its functions, and the principles, challenges, and strategies for RNA therapeutics.

Epigenetics is emerging as one of the most dynamic and vibrant biomedical areas. Multiple lines of evidence confirm that inherited genetic changes alone cannot fully explain all phenotypic characteristics of live organisms, and additional factors, which are not encoded in the DNA sequence, are involved. The contribution of non-genetic factors is…

Since biomedical science has become increasingly data-intensive, acquisition of computational and quantitative skills by science students has become more important. For non-science students, an introduction to biomedical databases and their applications promotes the development of a scientifically literate population. Because typical college…

Nanoscale science and engineering are disciplines that examine the unique behaviors and properties of materials that emerge at the size range of 1 to 100 nanometers (a billionth of a meter). Nanobiotechnology is a sub-discipline of nanoscience that has arisen more recently. Nanobiotechnology is already impacting the fields of healthcare and…

Mycobacteriophages are in the limelight of biomedical science (Pedulla et al., 2003), and new phage can be discovered and studied in a variety of high school and undergraduate educational settings. Simple methods for finding and studying new mycobacteriophage are described.

Describes early scientific research involving marine invertebrate pathologic processes that may have led to new insights into human disease. Discussed are inquiries of Metchnikoff, Loeb, and Cantacuzene (immunolgic responses in sea stars, horseshoe crabs, and marine worms, respectively). Describes current research stemming from these early…

Points out the fact that women and minority groups are underrepresented in the biomedical sciences. Investigates the effects of exposure to scientists from different careers with various life styles on students' attitudes toward science. Uses a questionnaire designed to evaluate student attitudes towards biomedical scientists. (YDS)

Details a simulation that employs a paper-and-pencil model to demonstrate the principles behind automated DNA sequencing. Discusses the advantages of automated sequencing as well as the chemistry of automated DNA sequencing. (DDR)

Describes a project that began as workshops for teachers in biotechnology and became a program that enables students to do hands-on biotechnology experiments in the classroom. The three parts of this program include the development of activities, access to equipment, and further workshops. (DDR)

Describes a laboratory protocol optimizing the conditions for the assay of pepsin activity using the Coomasie Blue dye binding assay of protein concentration. The dye bonds through strong, noncovalent interactions to basic and aromatic amino acid residues. (DDR)

Discusses applications of recombinant DNA technology and the controversies surrounding that technique. Provides a cooperative learning project idea that involves teams of students investigating and debating these issues. (DDR)