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The Association between Children's Autism Spectrum Disorders and Central Nervous System Infections: Using a Nationwide Claims Database
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Takanori Yanai; Satomi Yoshida; Koji Kawakami – Journal of Autism and Developmental Disorders, 2025
Several studies have reported an association of autism spectrum disorder (ASD) with central nervous system (CNS) infections and intrauterine infections; however, the results remain unclear. This study aimed to examine this issue using an extensive national database. Utilizing JMDC medical claims database, we conducted a retrospective cohort study…
Descriptors: Autism Spectrum Disorders, Microbiology, Neurology, Children
Brief Report: Plasma Leptin and Mealtime Feeding Behaviors among Children with Autism Spectrum Disorder: A Pilot Study
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Dhaliwal, Khushmol K.; Avedzi, Hayford M.; Richard, Caroline; Zwaigenbaum, Lonnie; Haqq, Andrea M. – Journal of Autism and Developmental Disorders, 2023
We examined the relationship between weight status, appetite regulating hormones, and mealtime behaviors among children, (5-12 years old), diagnosed with Autism Spectrum Disorder (ASD) in a cross-sectional study. All (N = 21) completed anthropometry measurements and (n = 18) provided blood samples for hormone analysis. Mealtime behavior, dietary,…
Descriptors: Body Weight, Metabolism, Physiology, Eating Habits
The Combination of Food Approach and Food Avoidant Behaviors in Children with Autism Spectrum Disorder: "Selective Overeating"
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Nadeau, Monica V.; Richard, Emily; Wallace, Gregory L. – Journal of Autism and Developmental Disorders, 2022
Based on parent questionnaires, we demonstrate the presence of an eating pattern among children with autism spectrum disorder (ASD) that is characterized by both food selectivity and eating in the absence of hunger. Children with ASD were categorized as engaging in eating patterns of selective overeating, selective eating only, overeating only, or…
Descriptors: Eating Habits, Children, Autism, Pervasive Developmental Disorders
Association between Exposure of Children to General Anesthesia and Autism Spectrum Disorder
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Laporta, Mariana L.; Sprung, Juraj; Fejedelem, Caroline A.; Henning, Dustin T.; Weaver, Amy L.; Hanson, Andrew C.; Schroeder, Darrell R.; Myers, Scott M.; Voigt, Robert G.; Weingarten, Toby N.; Flick, Randall P.; Warner, David O. – Journal of Autism and Developmental Disorders, 2022
This study tested the hypothesis that exposure of children prior to their third birthday to procedures requiring general anesthesia is associated with an increased incidence of autism spectrum disorder (ASD) in later life. This study employed a nested, 1:2 matched-case control study design using ASD cases identified in a population-based birth…
Descriptors: Anesthesiology, Autism Spectrum Disorders, Correlation, Infants
Diagnostic and Physical Effects in Parasympathetic Response to Social Evaluation in Youth with and without Autism Spectrum Disorder
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Muscatello, Rachael A.; Kim, Ahra; Vandekar, Simon; Corbett, Blythe A. – Journal of Autism and Developmental Disorders, 2022
Individuals with autism spectrum disorder (ASD) may demonstrate atypical autonomic (ANS) responses; however, research remains inconsistent. This study examined parasympathetic response during social evaluation in 241 youth (10-13 years) with ASD (n = 138) or typical development (TD; n = 103). Diagnosis, age, pubertal development, and body mass…
Descriptors: Autism, Pervasive Developmental Disorders, Physiology, Neurological Organization
Weight Management Outcomes of Youth with Autism Spectrum Disorder Seeking Treatment from a Multidisciplinary Team
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Killian, Haley J.; Pallotto, Isabella K.; Sweeney, Brooke R.; Dreyer Gillette, Meredith L. – Journal of Autism and Developmental Disorders, 2022
Youth with Autism Spectrum Disorder (ASD) are at an increased risk for developing obesity when compared to their typically developing peers. Given higher prevalence of obesity in youth with ASD, understanding factors relating to success in obesity treatment provides insight into implementing efficacious treatments for youth. The current study…
Descriptors: Autism, Pervasive Developmental Disorders, At Risk Persons, Obesity
Brief Report: Obesogenic Behaviors of Children with Developmental Disabilities during Summer
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Brazendale, Keith; Brazendale, Allison B.; Garcia, Jeanette M.; Monroe, Courtney M.; Weaver, R. Glenn; Beets, Michael W. – Journal of Autism and Developmental Disorders, 2021
The 'Structured Days Hypothesis' suggests that children's obesogenic behaviors (e.g., activity, diet, sleep, and screen time) are less favorable during times when there is less-structure to a child's day (e.g., summer). To compare obesogenic behaviors of children with developmental disabilities (DD) during summer on days with differing amounts of…
Descriptors: Child Health, Health Behavior, Body Weight, Obesity
Parental Feeding Practices and Child-Related Factors Are Associated with Overweight and Obesity in Children and Adolescents with Autism Spectrum Disorder
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Eow, Shiang Yen; Gan, Wan Ying; Lim, Poh Ying; Awang, Hamidin; Mohd Shariff, Zalilah – Journal of Autism and Developmental Disorders, 2022
Atypical eating behaviors displayed by children with autism spectrum disorder (ASD) predispose them to unhealthy weight gain. We determined the factors associated with body weight status among 261 children with ASD (3-18 years) at nine autism intervention centers. Their mothers completed a self-administered questionnaire on sociodemographic…
Descriptors: Eating Disorders, Children, Adolescents, Autism
An Exploration of Physical and Phenotypic Characteristics of Bangladeshi Children with Autism Spectrum Disorder
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Rahaman, Md. Ashiquir; Lopa, Maksuda; Uddin, K. M. Furkan; Baqui, Md. Abdul; Keya, Selina Parvin; Faruk, Md. Omar; Sarker, Shaoli; Basiruzzaman, Mohammed; Islam, Mazharul; AlBanna, Ammar; Jahan, Nargis; Chowdhury, M. A. K. Azad; Saha, Narayan; Hussain, Manzoor; Colombi, Costanza; O'Rielly, Darren; Woodbury-Smith, Marc; Ghaziuddin, Mohammad; Rahman, Mohammad Mizanur; Uddin, Mohammed – Journal of Autism and Developmental Disorders, 2021
This study explored the physical and clinical phenotype of Bangladeshi children with autism spectrum disorder (ASD). A totally of 283 children who were referred for screening and administered Module 1 of the Autism Diagnostic Observation Schedule (ADOS) were included. Overall, 209 met the ADOS algorithmic cutoff for ASD. A trend for greater weight…
Descriptors: Foreign Countries, Genetics, Autism, Pervasive Developmental Disorders
A Pilot Study Investigating the Feasibility and Acceptability of a Parent-Only Behavioral Weight-Loss Treatment for Children with Autism Spectrum Disorder
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Matheson, Brittany E.; Drahota, Amy; Boutelle, Kerri N. – Journal of Autism and Developmental Disorders, 2019
Evidence-based weight-loss treatments for children with autism spectrum disorder (ASD) are lacking. Therefore, a parent-based weight-loss treatment for children with ASD (PBT-ASD) was developed. A pilot study was conducted to test the initial efficacy, feasibility, and acceptability of this intervention. Parents of 20 children with ASD and…
Descriptors: Children, Autism, Pervasive Developmental Disorders, Body Weight
Perinatal Factors Associated with Autism Spectrum Disorder in Jamaican Children
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Saroukhani, Sepideh; Samms-Vaughan, Maureen; Lee, MinJae; Bach, MacKinsey A.; Bressler, Jan; Hessabi, Manouchehr; Grove, Megan L.; Shakespeare-Pellington, Sydonnie; Loveland, Katherine A.; Rahbar, Mohammad H. – Journal of Autism and Developmental Disorders, 2020
Mode of delivery, preterm birth, and low birth weight (LBW) are hypothesized to be associated with autism spectrum disorder (ASD) in the offspring. Using data from 343 ASD cases (2-8 years) and their age- and sex-matched typically developing controls in Jamaica we investigated these hypotheses. Our statistical analyses revealed that the parish of…
Descriptors: Foreign Countries, Perinatal Influences, Autism, Pervasive Developmental Disorders
Differences in Body Mass Index (BMI) in Early Adolescents with Autism Spectrum Disorder Compared to Youth with Typical Development
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Corbett, Blythe A.; Muscatello, Rachael A.; Horrocks, Briana K.; Klemencic, Mark E.; Tanguturi, Yasas – Journal of Autism and Developmental Disorders, 2021
Adolescence is a time of exceptional physical health juxtaposed against significant psychosocial and weight-related problems. The study included 241, 10-to-13-year-old youth with autism spectrum disorder (ASD, N = 138) or typical development (TD, N = 103). Standardized exams measured pubertal development, height (HT), weight (WT), heart rate (HR),…
Descriptors: Autism, Pervasive Developmental Disorders, Body Composition, Body Weight
Trajectories of Change in the Behavioral and Health Phenotype of Adolescents and Adults with Fragile X Syndrome and Intellectual Disability: Longitudinal Trends over a Decade
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Usher, Lauren V.; DaWalt, Leann S.; Hong, Jinkuk; Greenberg, Jan S.; Mailick, Marsha R. – Journal of Autism and Developmental Disorders, 2020
This study examined trajectories of daily living skills, behavior problems, body mass index (BMI), and health conditions spanning nearly a decade in adolescents and adults with fragile X syndrome (N = 134; age range at study end = 19-49 years), examining influences of sex and autism spectrum disorder (ASD) symptoms. Hierarchical linear modeling…
Descriptors: Adolescents, Adults, Genetic Disorders, Gender Differences
Brief Report: Physical Activity, Body Mass Index and Arterial Stiffness in Children with Autism Spectrum Disorder: Preliminary Findings
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Heffernan, Kevin S.; Columna, Luis; Russo, Natalie; Myers, Beth A.; Ashby, Christine E.; Norris, Michael L.; Barreira, Tiago V. – Journal of Autism and Developmental Disorders, 2018
We examined the association between physical activity (PA), body mass index (BMI) and novel measures of subclinical cardiovascular disease (CVD) in 15 children with autism spectrum disorder (ASD) (mean age 7 ± 2 years, 2 girls). PA was objectively assessed using accelerometry as time spent in moderate-vigorous physical activity (MVPA). Arterial…
Descriptors: Autism, Pervasive Developmental Disorders, Children, Body Composition
Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review
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Jain, Seema; Andridge, Rebecca; Hellings, Jessica A. – Journal of Autism and Developmental Disorders, 2016
Loxapine substitution is a promising option for patients with autism spectrum disorder (ASD) who develop antipsychotic-induced metabolic illness. We performed a chart review of 15 adolescents and adults meeting DSM-IV-TR criteria for ASD, all with antipsychotic-associated weight gain, who received low dose loxapine in an attempt to taper or…
Descriptors: Autism, Pervasive Developmental Disorders, Drug Therapy, Adolescents
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