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Inhibition of Glycogen Synthase Kinase-3ß Enhances Cognitive Recovery after Stroke: The Role of TAK1
Peer reviewed
Direct linkVenna, Venugopal Reddy; Benashski, Sharon E.; Chauhan, Anjali; McCullough, Louise D. – Learning & Memory, 2015
Memory deficits are common among stroke survivors. Identifying neuroprotective agents that can prevent memory impairment or improve memory recovery is a vital area of research. Glycogen synthase kinase-3ß (GSK-3ß) is involved in several essential intracellular signaling pathways. Unlike many other kinases, GSK-3ß is active only when…
Descriptors: Memory, Neurological Impairments, Brain, Neurological Organization
Arnsten, Amy F. T.; Rubia, Katya – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: This article aims to review basic and clinical studies outlining the roles of prefrontal cortical (PFC) networks in the behavior and cognitive functions that are compromised in childhood neurodevelopmental disorders and how these map into the neuroimaging evidence of circuit abnormalities in these disorders. Method: Studies of animals,…
Descriptors: Evidence, Attention Deficit Hyperactivity Disorder, Anxiety Disorders, Brain Hemisphere Functions
