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Lee, Grace; Disterhoft, John F.; Kuo, Amy G. – Learning & Memory, 2006
A common cellular alteration, reduced post-burst afterhyperpolarization (AHP) in CA1 neurons, is associated with acquisition of the hippocampus-dependent tasks trace eyeblink conditioning and the Morris water maze. As a similar increase in excitability is correlated with these two learning paradigms, we sought to determine the interactive…
Descriptors: Behavioral Science Research, Conditioning, Neurological Organization, Brain
Rhodes, Sarah E. V.; Kilcross, Simon – Learning & Memory, 2004
The prefrontal cortex (PFC) has a well-established role in the inhibition of inappropriate responding, and evidence suggests that the infralimbic (IL) region of the rat medial PFC (MPFC) may be involved in some aspects of extinction of conditioned fear. MPFC lesions including, but not those sparing the IL cortex increase spontaneous recovery of…
Descriptors: Neurological Impairments, Neurological Organization, Brain, Behavioral Science Research