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Martig, Adria K.; Mizumori, Sheri J. Y. – Learning & Memory, 2011
The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) may provide modulatory signals that, respectively, influence hippocampal (HPC)- and striatal-dependent memory. Electrophysiological studies investigating neural correlates of learning and memory of dopamine (DA) neurons during classical conditioning tasks have found DA…
Descriptors: Classical Conditioning, Memory, Brain, Rewards
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Kheirbek, Mazen A.; Beeler, Jeff A.; Chi, Wanhao; Ishikawa, Yoshihiro; Zhuang, Xiaoxi – Learning & Memory, 2010
In appetitive Pavlovian learning, animals learn to associate discrete cues or environmental contexts with rewarding outcomes, and these cues and/or contexts can potentiate an ongoing instrumental response for reward. Although anatomical substrates underlying cued and contextual learning have been proposed, it remains unknown whether specific…
Descriptors: Learning, Animals, Cues, Classical Conditioning
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Cheng, Jingjun; Feenstra, Matthijs G. P. – Learning & Memory, 2006
Combined activation of dopamine D1- and NMDA-glutamate receptors in the nucleus accumbens has been strongly implicated in instrumental learning, the process in which an individual learns that a specific action has a wanted outcome. To assess dopaminergic activity, we presented rats with two sessions (30 trials each) of a one-lever appetitive…
Descriptors: Rewards, Biochemistry, Nonverbal Learning, Animals