Purpose: Hearing loss is associated with changes in brain volume in regions supporting auditory and cognitive processing. The purpose of this study was to determine whether there is a systematic association between hearing ability and brain volume in cross-sectional data from a large nonclinical cohort of middle-aged adults available from the UK…

Semantic ambiguity has been shown to slow comprehension, although it is unclear whether this ambiguity disadvantage is attributable to competition in semantic activation or difficulties in response selection. We tested the two accounts by examining semantic relatedness decisions to homonyms, or words with multiple unrelated meanings (e.g.,…

Research suggests that second language words are learned faster when they are similar in phonological structure or accent to the words of an individual's first language. Many major theories suggest this happens because of differences in frequency of exposure and context between first and second language words. Here, we examine the independent…

The first 1,000 days of life are a critical window of vulnerability to exposure to socioeconomic and health challenges (i.e. poverty/undernutrition). The Brain Imaging for Global Health (BRIGHT) project has been established to deliver longitudinal measures of brain development from 0 to 24 months in UK and Gambian infants and to assess the impact…

The perfective aspect marker in Chinese is partly functionally similar to inflectional suffixes in Indo-European languages but is non-inflectional and lexical in nature, lying thus at the semantics-syntax interface. This provides us with the opportunity to compare directly the syntactic and semantic constraints during second language (L2) sentence…

The question of "how we learn" continues to direct scholarly debate, yet undergraduate teaching is typically designed to homogenise the learning environment. This is despite heterogeneous learning outcomes ensuing for students, owing to their different learning styles. Accordingly, we examine the relationship between teaching…

The role of prosodic information in sentence processing is not usually addressed in second language (L2) instruction, and neurocognitive studies on prosody-syntax interactions are rare. Here we compare event-related potentials (ERP) of Chinese and German learners of English L2 to those of native English speakers and show how first language (L1)…

This article is the first of a two-part series that explores science teachers' and their pupils' experiences of using different pedagogical approaches based on understandings of how brains learn. For this case-study research, nine science teachers were interviewed and four teachers self-selected to trial a pedagogical approach, new to them, from…

This study investigated the neurobiological basis of comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD). We compared children with ASD, ADHD or ADHD+ASD and typically developing controls (CTRL) on behavioural and electrophysiological correlates of gaze cue and face processing. We measured effects…

Hyperventilation-induced high-amplitude rhythmic slow activity with altered awareness (HIHARS) is increasingly being identified in children and is thought to be an age-related non-epileptic electrographic phenomenon. We retrospectively investigated the clinical outcome in 15 children (six males, nine females) with HIHARS (mean age 7y, SD 1y 11mo;…

Numerous studies have shown that bilinguals presented with words in one of their languages spontaneously and automatically activate lexical representations from their other language. However, such effects, found in varied experimental contexts, both in behavioural and psychophysiological investigations, have been essentially limited to the…

Viewing another person's hand actions enhances excitability in an observer's left and right primary motor (M1) cortex. We aimed to determine whether viewing communicative hand actions alters this bilateral sensorimotor resonance. Using single-pulse transcranial magnetic stimulation (TMS), we measured excitability in the left and right M1 while…

Severe deprivation in the first few years of life is associated with multiple difficulties in cognition and behavior. However, the brain basis for these difficulties is poorly understood. Structural and functional neuroimaging studies have implicated limbic system structures as dysfunctional, and one functional imaging study in a heterogeneous…

Studies of spoken and signed language processing reliably show involvement of the posterior superior temporal cortex. This region is also reliably activated by observation of meaningless oral and manual actions. In this study we directly compared the extent to which activation in posterior superior temporal cortex is modulated by linguistic…

The adoption into the UK of children who have been reared in severely deprived conditions provides an opportunity to study possible association between very early negative experiences and subsequent brain development. This cross-sectional study was a pilot for a planned larger study quantifying the effects of early deprivation on later brain…