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Direct linkMaddox, Stephanie A.; Monsey, Melissa S.; Schafe, Glenn E. – Learning & Memory, 2011
The immediate-early gene early growth response gene-1 (EGR-1, zif-268) has been extensively studied in synaptic plasticity and memory formation in a variety of memory systems. However, a convincing role for EGR-1 in amygdala-dependent memory consolidation processes has yet to emerge. In the present study, we have examined the role of EGR-1 in the…
Descriptors: Classical Conditioning, Short Term Memory, Long Term Memory, Fear
Darvas, Martin; Fadok, Jonathan P.; Palmiter, Richard D. – Learning & Memory, 2011
Two-way active avoidance (2WAA) involves learning Pavlovian (association of a sound cue with a foot shock) and instrumental (shock avoidance) contingencies. To identify regions where dopamine (DA) is involved in mediating 2WAA, we restored DA signaling in specific brain areas of dopamine-deficient (DD) mice by local reactivation of conditionally…
Descriptors: Animals, Classical Conditioning, Genetics, Biochemistry
