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Direct linkYi-Ling Chien; Yi-Li Tseng; Wen-Che Tsai; Yen-Nan Chiu – Journal of Autism and Developmental Disorders, 2025
This study applied the functional near-infrared spectroscopy (fNIRS) to investigate frontal activity in autism when performing verbal fluency test and emotion recall task. We recruited 32 autistic adults without intellectual disability and 30 typically-developing controls (TDC). Prefrontal hemodynamic changes were evaluated by fNIRS when the…
Descriptors: Spectroscopy, Brain Hemisphere Functions, Autism Spectrum Disorders, Emotional Response
Banu Ahtam; Hyuk Jin Yun; Rutvi Vyas; Rudolph Pienaar; Josephine H. Wilson; Caroline P. Goswami; Laura F. Berto; Simon K. Warfield; Mustafa Sahin; P. Ellen Grant; Jurriaan M. Peters; Kiho Im – Journal of Autism and Developmental Disorders, 2024
A significant number of individuals with tuberous sclerosis complex (TSC) exhibit language difficulties. Here, we examined the language-related brain morphometry in 59 participants (7 participants with TSC and comorbid autism spectrum disorder (ASD) (TSC + ASD), 13 with TSC but no ASD (TSC-ASD), 10 with ASD-only (ASD), and 29 typically developing…
Descriptors: Morphology (Languages), Autism Spectrum Disorders, Genetic Disorders, Brain Hemisphere Functions
Rabelo, Livia Nascimento; Queiroz, José Pablo Gonçalves; Castro, Carla Cristina Miranda; Silva, Sayonara Pereira; Campos, Laura Damasceno; Silva, Larissa Camila; Nascimento, Ezequiel Batista; Martínez-Cerdeño, Veronica; Fiuza, Felipe Porto – Journal of Autism and Developmental Disorders, 2023
Autism spectrum disorder (ASD) is manifested by abnormal cell numbers and patches of gene expression disruption in higher-order brain regions. Here, we investigated whether layer-specific changes in glia/neuron ratios (GNR) characterize patches in the dorsolateral prefrontal cortex (DL-PFC) of children with ASD. We analyzed high-resolution digital…
Descriptors: Autism Spectrum Disorders, Brain Hemisphere Functions, Children, Neurodevelopmental Disorders
Yukihiko Shirayama; Kazuki Matsumoto; Fumio Osone; Akira Hara; Siqing Guan; Sayo Hamatani; Katsumasa Muneoka; Koichi Sato; Akihiro Okada; Tokuzou Yokokawa – Journal of Autism and Developmental Disorders, 2024
Proton magnetic resonance spectroscopy ([superscript 1]H-MRS) has shown inconsistent alterations in brain metabolites of adults with autism spectrum disorder (ASD). We investigated brain metabolites in the medial prefrontal cortex and amygdala of 24 drug-naive adults with ASD and no intellectual disability and 24 non-ASD control subjects, using…
Descriptors: Brain, Brain Hemisphere Functions, Adults, Autism Spectrum Disorders
Han-xue Yang; Yi-jing Zhang; Hui-xin Hu; Ling-ling Wang; Yong-jie Yan; Simon S. Y. Lui; Yi Wang; Raymond C. K. Chan – Journal of Autism and Developmental Disorders, 2024
Interoception, the sense of the physiological condition of our body, is impaired in individuals with autism spectrum disorders. Evidence suggests that subclinical autistic traits are mild manifestations of autistic symptoms, present in the general population. We examined the resting-state functional connectivity (rsFC) associating with…
Descriptors: Autism Spectrum Disorders, Symptoms (Individual Disorders), Physiology, Sensory Experience
Christiana Butera; Jonathan Delafield-Butt; Szu-Ching Lu; Krzysztof Sobota; Timothy McGowan; Laura Harrison; Emily Kilroy; Aditya Jayashankar; Lisa Aziz-Zadeh – Journal of Autism and Developmental Disorders, 2025
Autism spectrum disorder (ASD) and Developmental Coordination Disorder (DCD) are distinct clinical groups with overlapping motor features. We attempted to (1) differentiate children with ASD from those with DCD, and from those typically developing (TD) (ages 8-17; 18 ASD, 16 DCD, 20 TD) using a 5-min coloring game on a smart tablet and (2)…
Descriptors: Autism Spectrum Disorders, Developmental Disabilities, Psychomotor Skills, Children
Christine M. Falter-Wagner; Christian M. Kiefer; Anthony J. Bailey; Kai Vogeley; Jürgen Dammers – Journal of Autism and Developmental Disorders, 2024
Visual information is organised according to visual grouping principles. In visual grouping tasks individuals with ASD have shown equivocal performance. We explored neural correlates of Gestalt grouping in individuals with and without ASD. Neuromagnetic activity of individuals with (15) and without (18) ASD was compared during a visual grouping…
Descriptors: Autism Spectrum Disorders, Visual Perception, Cognitive Processes, Diagnostic Tests
Magdalena del Río; Chris Racey; Zhiting Ren; Jiang Qiu; Hao-Ting Wang; Jamie Ward – Journal of Autism and Developmental Disorders, 2024
Insofar as the autistic-like phenotype presents in the general population, it consists of partially dissociable traits, such as social and sensory issues. Here, we investigate individual differences in cortical organisation related to autistic-like traits. Connectome gradient decomposition based on resting state fMRI data reliably reveals a…
Descriptors: Autism Spectrum Disorders, Sensory Experience, Foreign Countries, Symptoms (Individual Disorders)
Tavares, Vânia; Fernandes, Luís Afonso; Antunes, Marília; Ferreira, Hugo; Prata, Diana – Journal of Autism and Developmental Disorders, 2022
Functional brain connectivity (FBC) has previously been examined in autism spectrum disorder (ASD) between-resting-state networks (RSNs) using a highly sensitive and reproducible hypothesis-free approach. However, results have been inconsistent and sex differences have only recently been taken into consideration using this approach. We estimated…
Descriptors: Brain Hemisphere Functions, Autism, Pervasive Developmental Disorders, Gender Differences
Papri Saha – Journal of Autism and Developmental Disorders, 2024
With the budding interests of structural and functional network characteristics as potential parameters for abnormal brains, an essential and thus simpler representation and evaluations have become necessary. Eigenvector centrality measure of functional magnetic resonance imaging ("fMRI") offer region wise network representations through…
Descriptors: Autism Spectrum Disorders, Brain, Diagnostic Tests, Models
Amanda Cremone-Caira; Yael Braverman; Gabrielle A. MacNaughton; Julia I. Nikolaeva; Susan Faja – Journal of Autism and Developmental Disorders, 2024
Provided the significant overlap in features of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), there is a critical need to identify transdiagnostic markers that could meaningfully stratify subgroups. The objective of this study was to compare the visual evoked potential (VEP) between 30 autistic children, 17…
Descriptors: Autism Spectrum Disorders, Attention Deficit Hyperactivity Disorder, Symptoms (Individual Disorders), Children
Sanders, Ashley F. P.; Hobbs, Diana A.; Knaus, Tracey A.; Beaton, Elliott A. – Journal of Autism and Developmental Disorders, 2023
Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) exhibit impaired ability to process and understand emotions in others. We measured structural connectivity in children and adolescents with 22q11.2DS (n = 28) and healthy controls (n = 29). Compared to controls, those with 22q11.2DS had poorer social skills and more difficulty…
Descriptors: Genetic Disorders, Emotional Response, Children, Adolescents
Dongyue Zhou; Zhimei Liu; Guanyu Gong; Yunge Zhang; Lin Lin; Kelong Cai; Huashuai Xu; Fengyu Cong; Huanjie Li; Aiguo Chen – Journal of Autism and Developmental Disorders, 2024
Exercise intervention has been proven helpful to ameliorate core symptoms of Autism Spectrum Disorder (ASD). However, the underlying mechanisms are not fully understood. In this study, we carried out a 12-week mini-basketball training program (MBTP) on ASD children and examined the changes of brain functional and structural networks before and…
Descriptors: Exercise, Intervention, Symptoms (Individual Disorders), Autism Spectrum Disorders
Green, Heather L.; Shen, Guannan; Franzen, Rose E.; Mcnamee, Marybeth; Berman, Jeffrey I.; Mowad, Theresa G.; Ku, Matthew; Bloy, Luke; Liu, Song; Chen, Yu-Han; Airey, Megan; McBride, Emma; Goldin, Sophia; Dipiero, Marissa A.; Blaskey, Lisa; Kuschner, Emily S.; Kim, Mina; Konka, Kimberly; Roberts, Timothy P. L.; Edgar, J. Christopher – Journal of Autism and Developmental Disorders, 2023
Maturation of auditory cortex neural encoding processes was assessed in children with typical development (TD) and autism. Children 6-9 years old were enrolled at Time 1 (T1), with follow-up data obtained ~ 18 months later at Time 2 (T2), and ~ 36 months later at Time 3 (T3). Findings suggested an initial period of rapid auditory cortex maturation…
Descriptors: Brain Hemisphere Functions, Autism Spectrum Disorders, Young Children, Auditory Perception
Cora E. Mukerji; John S. Wilson III; Carol L. Wilkinson; Manon A. Krol; Charles A. Nelson; Helen Tager-Flusberg – Journal of Autism and Developmental Disorders, 2025
Previous research links resting frontal gamma power to key developmental outcomes in young neurotypical (NT) children and infants at risk for language impairment. However, it remains unclear whether gamma power is specifically associated with language or with more general cognitive abilities among young children diagnosed with autism spectrum…
Descriptors: Brain Hemisphere Functions, Language Impairments, Neurological Impairments, Young Children
