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Direct linkDavies, Don A.; Hurtubise, Jessica L.; Greba, Quentin; Howland, John G. – Learning & Memory, 2017
The trial-unique, delayed nonmatching-to-location (TUNL) task is a recently developed behavioral task that measures spatial working memory and a form of pattern separation in touchscreen-equipped operant conditioning chambers. Limited information exists regarding the neurotransmitters and neural substrates involved in the task. The present…
Descriptors: Brain Hemisphere Functions, Brain, Short Term Memory, Neurological Organization
Bas-Orth, Carlos; Tan, Yan-Wei; Oliveira, Ana M. M.; Bengtson, C. Peter; Bading, Hilmar – Learning & Memory, 2016
The formation of long-term memory requires signaling from the synapse to the nucleus to mediate neuronal activity-dependent gene transcription. Synapse-to-nucleus communication is initiated by influx of calcium ions through synaptic NMDA receptors and/or L-type voltage-gated calcium channels and involves the activation of transcription factors by…
Descriptors: Long Term Memory, Brain Hemisphere Functions, Animals, Genetics
Remaud, Jessica; Ceccom, Johnatan; Carponcy, Julien; Dugué, Laura; Menchon, Gregory; Pech, Stéphane; Halley, Helene; Francés, Bernard; Dahan, Lionel – Learning & Memory, 2014
Protein synthesis is involved in the consolidation of short-term memory into long-term memory. Previous electrophysiological data concerning LTP in CA3 suggest that protein synthesis in that region might also be necessary for short-term memory. We tested this hypothesis by locally injecting the protein synthesis inhibitor anisomycin in hippocampal…
Descriptors: Short Term Memory, Long Term Memory, Physiology, Hypothesis Testing
Maddox, Stephanie A.; Monsey, Melissa S.; Schafe, Glenn E. – Learning & Memory, 2011
The immediate-early gene early growth response gene-1 (EGR-1, zif-268) has been extensively studied in synaptic plasticity and memory formation in a variety of memory systems. However, a convincing role for EGR-1 in amygdala-dependent memory consolidation processes has yet to emerge. In the present study, we have examined the role of EGR-1 in the…
Descriptors: Classical Conditioning, Short Term Memory, Long Term Memory, Fear
