This research was carried out to examine the mediating role of job satisfaction in the effect of physical education teachers' leader-member exchange on burnout. As data collection tools, leader-member exchange, job satisfaction and the Maslach burnout scale were used. The study group of the research consists of a total of 155 physical education teachers who work in Malatya and Hatay provinces of Turkey. The study group was selected with the convenience sampling method, one of the non-random sampling methods. A questionnaire was applied to the teachers participating in the research via electronic communication tools. Data obtained from participants were analyzed using SPSS Amos 20.0 and Process macro. In the research, descriptive statistics, correlation, confirmatory factor analysis, and bootstrap regression analysis were performed. As a result of this study, it was found that job satisfaction played a mediating role in the effect of leader-member exchange on physical education teachers' burnout levels. It can be stated that increasing physical education teachers' leader-member exchange and improving their relationships with their superiors can effectively increase job satisfaction and reduce burnout.