Argues for the use of procedures known as clearing and double staining to clear soft tissues and differentially stain cartilage and bone in specimens. Describes each step of the process. (DDR)

Discussed are modifications in data analysis that allow Gran plot methodology to be extended to acidic or basic analyte solutions that would be difficult to treat by conventional equations. (RH)

A method of estimating the solubilities of drugs in water is reported that is based on a principle applied in quantitative structure-activity relationships. This procedure involves correlation of partition coefficient values using the octanol/water system and aqueous solubility. (Author/MLW)

Explains the procedures used to determine the regulatory properties of yeast pyruvate kinase. Involves a partial purification using PEG precipitation that can be done in one laboratory period with simple equipment. (DDR)

Discusses a laboratory exercise (suitable for the day before spring vacation) involving use of a hard-boiled egg to stimulate student responses to questions on the effect of adding salt to the water, formation of iron sulfide, ease of peeling, and gas laws. Additional experiments are included. (BC)

Explains an experiment that can be used to help students visualize the phase changes of carbon dioxide. The equipment consists of tweezers and a small plastic syringe. Dry ice is also required. Results are discussed and the phase diagram for carbon dioxide is provided. (DDR)

Provides background information and procedures for the multi-step synthesis of tiger moth and boll weevil pheromones (sex attractants). These syntheses require several laboratory periods. The tiger moth pheromone synthesis is suitable for introductory organic chemistry while the boll weevil pheromone is recommended for an advanced laboratory…

Describes a senior-level experiment dealing with the synthesis and characterization of a perovskite. Since most perovskites are cubic, their characterization by x-ray diffraction is simplified. In addition, magnetic ordering may be observed and the effects of a Jahn-Teller distortion seen. (JN)

Describes experiments using dye solutions in liquid crystals in which polar molecules are oriented in an electrical field and devices are constructed to change their color in response to an electric signal. (CS)

Presents background information, safety notes, and laboratory procedures for synthesizing dinitrogen and dihydrogen complexes of molybdenum. The one-step method described is suitable for advanced inorganic chemistry classes. (SK)

Describes a procedure for the synthesis and characterization of cobalt (III) complexes in one 6-hour laboratory period. Hydrogen peroxide is used for speeding up the preparation of these complexes if solutions are heated to complete the reaction. (Author/JN)

Describes a demonstration that illustrates the reversibility of thermal reactions using a gas burner and copper sulfate. Explains the procedure and provides tips to guide student thinking. (DDR)

Describes a demonstration known as Elephant's Toothpaste in which the decomposition of hydrogen peroxide is catalyzed by iodide. Oxygen is released and soap bubbles are produced. The foam produced is measured, and results show a good relationship between the amount of foam and the concentration of the hydrogen peroxide. (DDR)

The use of the thiosulfate ion in teaching the concepts of gas formation, precipitate formation, complex formation, acid-base interaction, redox interaction, time evolution of chemical processes, catalysis, and stoichiometry is discussed. Several demonstrations and activities are detailed. (CW)

Presents demonstrations of chemical reactions by employing different features of various compounds that can be altered after a chemical change occurs. Experimental activities include para- and dia-magnetism in chemical reactions, aluminum reaction with base, reaction of acid with carbonates, use of electrochemical cells for demonstrating chemical…