Describes recent attempts to program computers to map synthetic routes to organic compounds. The computer is provided with structural information for many molecules and reaction descriptions; when a target compound is specified, the computer lists possible precursors, thus indicating possible synthetic routes. (MLH)

Described are two microscale chemistry laboratory experiments including "Microscale Syntheses of Heterocyclic Compounds," and "Microscale Acid-Base Extraction--A Colorful Introduction." Materials, procedures and probable results are discussed. (CW)

The entropy change for a reaction in aqueous solution can be evaluated as a combination of entropy factors. Valuable insight or understanding can be obtained from a detailed examination of these factors. Several entropy effects of inorganic chemical reactions are discussed as examples. (Author/JN)

Discusses the molecular features common to compounds which taste sweet. Particular emphasis is placed on the hydrogen bonding evident in these chemicals. (TS)

Concerted reactions occur in only one step and thus present special problems in the study of their reaction mechanisms. Concertedness can be established with certainty only from a detailed description of the transition state. (Author/TS)

Describes procedures suitable for student preparation of benzaldehyde, benzoic acid, and ethyl benzoate sequentially from benzyl alcohol. Preparation for benzyl chloride also given. All reagents except benzyl alcohol are common inorganic chemicals. (AL)

Explains the reason that chemistry of carbon using principles of bonding, thermodynamics, and kinetics is considered a better introduction to organic chemistry than conventional use of interconversions. (DS)

A discussion is presented of the toxicity, chemistry, and environmental presence of nitrosamines. Carcinogenicity and effects on various organs of test animals are reviewed. Also some information on the presence of use of nitrosamines in human food is given. (MR)