The chlorination reaction of aromatic compounds is highly important for the synthesis of pharmaceutical products. As the most common chlorination reagent, chlorine is restricted from undergraduate laboratory experiment training due to its toxicity. In this work, we reported the chlorination of aromatic compounds with chlorine generated from the…

The inductive effect is one of the very important concepts of electronic effects in organic chemistry. In traditional teaching methods, only the origin, transmission mode, and decay of the inductive effect are introduced briefly, which is not conducive to students' complete understanding of the inductive effect. This work developed a new method to…

In this paper, we propose a novel method for deriving Russell-Saunders terms of complex atomic systems with an arbitrary number of equivalent electrons in orbitals with a higher azimuthal number. The method can be regarded as an extension of the classic works of Douglas, McDaniel, and Hyde but with several notable improvements, including the…

By organizing an extracurricular seminar, based on the analysis of the intermolecular dispersion action in normal alkanes, a new topological index (named "Intermolecular Interaction Index (IMI)") was proposed to express the intermolecular dispersion force. The IMI has an excellent linear relationship with the boiling point (T[subscript…

In organic chemistry textbooks (S)-(-)-limonene, (-)-limonene or l-limonene, is often given credit for the smell of lemons, while the R-analogue, (+)-limonene or d-limonene, is credited with that of oranges. Results from two odor tests revealed that few persons in the test associated (R)-(+)-limonene with oranges and (S)-(-)-limonene with lemons,…

In this experiment, students explore the synthesis and physical property characterization of the magnetic material strontium hexaferrite (SrFe[subscript 12]O[subscript 19]). SrFe[subscript 12]O[subscript 19] crystallites are prepared by a simple but fascinating sol-gel autocombustion synthesis. The prepared powder is compacted into pellets and…

Pedagogical research over the past decade has shown that chemistry courses have high failure rates and low accessibility. The implementation of novel active-learning approaches has great potential to offset these trends. Fundamental concepts that serve as "pinch points" are ripe targets for designing innovative, gamified course materials…

Studies investigating chemistry students' understanding of intermolecular forces have listed alternative conceptions; however, there is a call to investigate why students might have these alternative conceptions. This study describes how second semester general chemistry students predict the location of dipole-dipole forces between two molecules…

VibHam is an adaptable and user-friendly program designed for advanced diatomic molecule spectroscopy beyond the harmonic oscillator approximation. It employs numerical solutions to the rovibrational Schrödinger equation, accurately reproducing spectroscopic constants and offering insights into rovibrational wave functions, energy levels, and…

Owing to factors such as poor water solubility of luminol and the instability and easy decomposition of hydrogen peroxide (H[subscript 2]O[subscript 2]), the accuracy and sensitivity of the detection of H[subscript 2]O[subscript 2] through the luminol electrochemiluminescence (ECL) system are limited. Herein, we propose a water-soluble…

A laboratory experiment has been designed for teaching laboratories aimed at training students in the basics of spectroscopy in junior and senior level undergraduate chemistry courses. Despite the ubiquity of light-based tools in modern science, students often find it difficult to comprehend light and light-matter interactions. A portable…

Spectroscopy is an integral part of chemical research, and the operation of any spectroscopic instrument is critical in chemical education. This study presents a low-cost, do-it-yourself (DIY) style spectrophotometer system that can be adapted for UV--vis spectrophotometry, fluorimetry, and atomic emission spectroscopy applications. The DIY system…

The subject of pharmaceutical research has traditionally focused on drugs with systemic effects. However, contemporary approaches aspire to achieve targeted drug delivery, with the aim of combatting infections with a precise immune response. Active substances are encapsulated in nanoparticles, transported through the body, and selectively released…

This article reports the development of Chem'Sc@pe, an escape game activity for first- and second-year undergraduate students, covering various topics from an introductory organic chemistry course. The objective was to encourage them to review notions learned in class in a fun and collaborative environment. The set comprises a game board…

Different molecular representations are usually used to depict the three-dimensional (3D) structure of organic compounds. Mastering the skill of interconverting one form into another is essential for students to ensure success in organic chemistry. The traditional and recently developed methods for completing such interconversions that rely on 3D…