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Direct linkJennie Sotelo-Orozco; Irva Hertz-Picciotto – Journal of Autism and Developmental Disorders, 2025
Investigate the association between gastrointestinal (GI) issues and psychometric scores among children with developmental delays and typical development. We examined the association between GI issues and the Mullen Scale of Early Learning (MSEL), Vineland Adaptive Behavior Subscales (VABS), and Aberrant Behavior Checklist (ABC) scores from…
Descriptors: Autism Spectrum Disorders, Physiology, Developmental Delays, Down Syndrome
Shurtz, Logan; Schwartz, Chloe; DiStefano, Charlotte; McPartland, James C.; Levin, April R.; Dawson, Geraldine; Kleinhans, Natalia M.; Faja, Susan; Webb, Sara J.; Shic, Frederick; Naples, Adam J.; Seow, Helen; Bernier, Raphael A.; Chawarska, Katarzyna; Sugar, Catherine A.; Dziura, James; Senturk, Damla; Santhosh, Megha; Jeste, Shafali S. – Autism: The International Journal of Research and Practice, 2023
Children with autism spectrum disorder are prescribed various medications to address behavior and mood. In clinical trials, individuals taking concomitant psychotropic medications often are excluded to maintain homogeneity and prevent contamination of clinical endpoints. However, this choice may compromise the representativeness of the sample. In…
Descriptors: Autism Spectrum Disorders, Drug Therapy, Incidence, Child Behavior
Srivastava, Siddharth; Clark, Bennett; Landy-Schmitt, Colleen; Offermann, Elizabeth A.; Kline, Antonie D.; Wilkinson, Samuel T.; Grados, Marco A. – Journal of Autism and Developmental Disorders, 2021
Cornelia de Lange syndrome (CdLS) is associated with repetitive and self-injurious behaviors (RBs, SIB). Evaluating children with CdLS, this study: (1) characterizes the spectrum of RBs; (2) characterizes the impact and severity of RBs including SIB; (3) describes how age and adaptive functioning relate to RBs including SIB. Fifty children…
Descriptors: Behavior Problems, Self Destructive Behavior, Genetic Disorders, Intellectual Disability
Alison Fong; Robin Friedlander; Anamaria Richardson; Katie Allen; Qian Zhang – International Journal of Developmental Disabilities, 2024
Objective: This study aims to delineate the characteristics of severe self-injurious behaviors (SIB) in a cohort of children with autism and unspecified intellectual developmental disorder (UIDD) (intellectual disability) and examine potential risk factors for developing SIB. Methods: A retrospective chart review studied characteristics of severe…
Descriptors: Self Destructive Behavior, Children, Autism Spectrum Disorders, Developmental Disabilities
Mindy Scheithauer; Joanna Lomas Mevers; Lawrence Scahill; Sarah Slocum Freeman; Colin Muething; Chelsea Rock; Scott Gillespie; Laura Johnson; Nathan Call – Autism: The International Journal of Research and Practice, 2025
Elopement is a common and dangerous behavior among autistic children. Behavioral treatments can reduce elopement, but most evidence comes from small-N evaluations in specialized settings with strategies varying across studies. The current study compared the efficacy of the caregiver-mediated function-based elopement treatment to parent education…
Descriptors: Behavior Problems, Children, Preadolescents, Autism Spectrum Disorders
McCrae, Christina S.; Chan, Wai Sze; Curtis, Ashley F.; Nair, Neetu; Deroche, Chelsea B.; Munoz, Melissa; Takamatsu, Stephanie; McLean, Deija; Davenport, Mattina; Muckerman, Julie E.; Takahashi, Nicole; McCann, Dillon; McGovney, Kevin; Sahota, Pradeep; Mazurek, Micah O. – Autism: The International Journal of Research and Practice, 2021
Insomnia is common in children with autism. Cognitive behavioral treatment for childhood insomnia may improve sleep and functioning in children with autism and their parents, but delivery involving multiple office visits limits accessibility. This single-arm pilot study tested telehealth delivery of eight-session cognitive behavioral treatment for…
Descriptors: Autism, Pervasive Developmental Disorders, Sleep, Cognitive Restructuring
Scheithauer, Mindy; Call, Nathan A.; Lomas Mevers, Joanna; McCracken, Courtney E.; Scahill, Lawrence – Journal of Autism and Developmental Disorders, 2021
Elopement is a common and dangerous concern in autism spectrum disorder (ASD). There is evidence that behavior analytic treatments can successfully treat elopement, but the research is limited due to small samples and treatment components varying across studies. The current study evaluated the feasibility of studying a manualized intervention for…
Descriptors: Randomized Controlled Trials, Intervention, Behavior Problems, Children
Serdar Karatoprak; Sadettin Burak Acikel; Abdulbaki Akyildiz; Fatma Coskun; Fatma Hümeyra Yerlikaya – International Journal of Developmental Disabilities, 2024
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder, the etiology of which has not been clearly determined yet. There is increasing evidence that synaptic and dendritic changes are involved in the etiology of ASD. The aim of this study is to determine whether serum Thrombospondin-1 and Thrombospondin-2 differ between ASD…
Descriptors: Children, Autism Spectrum Disorders, Etiology, Metabolism
Masahiko Inoue; Yoichi Gomi; Soichiro Matsuda – International Journal of Developmental Disabilities, 2024
Introduction: Individuals with intellectual disabilities (ID) are at heightened risk of behavioral problems. Methods: This study investigated differences in the severity of challenging behaviors (CBs) among individuals with IDs at varying life stages. Data were collected from parents' retrospective interviews. Surveys were completed by 47 parents…
Descriptors: Foreign Countries, Intellectual Disability, Adults, Children
Annemieke Hoogstad; Liesbeth Mevissen; Robert Didden – Journal of Developmental and Physical Disabilities, 2024
No research has been conducted on PTSD manifestation in children with severe or moderate intellectual disability (SID; IQ 20-49) and no PTSD measurement instrument was available. This pilot explores the psychometric properties of a new diagnostic instrument to investigate trauma and to classify PTSD in children with SID. The Diagnostic Interview…
Descriptors: Posttraumatic Stress Disorder, Children, Severe Intellectual Disability, Moderate Intellectual Disability
Lloyd, Blair P.; Weaver, Emily S.; Torelli, Jessica N.; Pollack, Marney S.; Fareed, Sunya A.; Maxwell-Horn, Angela C. – American Journal on Intellectual and Developmental Disabilities, 2021
The purpose of the current study was to explore the scientific utility of two behavior analytic assessments (i.e., progressive ratio and demand assessments) for psychotropic medication evaluation. For a sample of 23 children with disabilities who were prescribed medication, we conducted a series of generalizability and optimization studies to…
Descriptors: Disabilities, Children, Drug Therapy, Behavior Problems
Halvorsen, Marianne; Aman, Michael G.; Mathiassen, Børge; Brøndbo, Per Håkan; Steinsvik, Oddmar Ole; Martinussen, Monica – Journal of Mental Health Research in Intellectual Disabilities, 2019
Introduction: Although the Aberrant Behavior Checklist (ABC) is one of the most widely used behavioral rating scales among people with developmental disabilities, very few studies have examined the factor structure of the non-English versions. Methods: The construct validity of the Norwegian ABC was examined in a clinical sample of children and…
Descriptors: Foreign Countries, Check Lists, Behavior Problems, Psychometrics
Latent Class Analysis Identifies Distinctive Behavioral Subtypes in Children with Fragile X Syndrome
Walter E. Kaufmann; Melissa Raspa; Carla M. Bann; Julia M. Gable; Holly K. Harris; Dejan B. Budimirovic; Reymundo Lozano – Journal of Autism and Developmental Disorders, 2024
Fragile X syndrome (FXS) is characterized by variable neurobehavioral abnormalities, which leads to difficulties in developing and evaluating treatments and in determining accurate prognosis. We employed a pediatric cross-sectional sample (1,072 males, 338 females) from FORWARD, a clinic-based natural history study, to identify behavioral subtypes…
Descriptors: Symptoms (Individual Disorders), Children, Genetic Disorders, Intellectual Disability
Dean, Olivia M.; Gray, Kylie; Dodd, Seetal; Villagonzalo, Kristi-Ann; Brown, Ellie; Tonge, Bruce; Berk, Michael; Byrne, Linda K. – Journal of Intellectual & Developmental Disability, 2019
Background: Traditional treatment for the behavioural symptoms in autism spectrum disorder (ASD) remains unsatisfactory. There is an urgent need for new, biologically relevant therapies that target both the core and comorbid symptoms that children may experience. This article builds on research previously published by the authors. Method: We…
Descriptors: Autism, Pervasive Developmental Disorders, Intervention, Children
Reliability and Validity of the Pediatric Anxiety Rating Scale Modified for Autism Spectrum Disorder
Maddox, Brenna B.; Lecavalier, Luc; Miller, Judith S.; Pritchett, Jill; Hollway, Jill; White, Susan W.; Gillespie, Scott; Evans, Andrea N.; Schultz, Robert T.; Herrington, John D.; Bearss, Karen; Scahill, Lawrence – Autism: The International Journal of Research and Practice, 2020
Anxiety often co-occurs with autism spectrum disorder, yet there are few valid and reliable instruments for measuring anxiety in youth with autism spectrum disorder. This article describes the modification of the Pediatric Anxiety Rating Scale for youth with autism spectrum disorder and systematic psychometric evaluation in a well-characterized…
Descriptors: Anxiety, Children, Adolescents, Rating Scales
